Abstract Introduction: Achievement of new drugs with minimal side effects is a important goal in the cancer treatment due to irreversible side effects of conventional drugs. Tricalcium phosphates as natural bone components have unique characteristics including excellent biocompatibility, high biosorption and superior bioactivity. This research aimed at investigating the inhibitory effect of tr...

This review focuses on the advances made in synthesis and application of hydroxyapatite (HA)- ?-tricalcium phosphate (?-TCP)-based composites for biomedical purposes, with placed both laboratory exploration clinical translation. First, polymeric matrix materials are reviewed, comparisons between naturally- synthetically-derived polymers briefly introduced. Second, calcium phosphates used hard t...

The effects of solid state synthesis process parameters (time and temperature) and primary calcium precursor on the amount of produced α-tricalcium phosphate (Ca3(PO4)2 or α -TCP) have been investigated. α-TCP was synthesized by firing of stoichiometric amount of calcium carbonate and monetite in first group and calcium carbonate and brushite in the second group, once at 1350°C for 3,6,8,16 h d...

The objective of this in-vitro study is evaluation remineralization potential three agents- Tricalcium phosphate flouride(TCP-F), Calcium sucrose phosphate(CaSP), Casein phosphopeptide- amorphous calcium phosphate(CPP-ACP) in artificial enamel lesion using laser fluorescence based DIAGNOdent(KaVo). 30 single rooted premolars were selected. Samples randomly divided into 3 groups with 10 samples ...

A simple route for synthesizing nano-sized beta-tricalcium phosphate (beta-TCP) at room temperature has been developed in methanol solvent. The phase evolution from CaHPO4, intermediate amorphous calcium phosphate (ACP) phases (including ACP1 and ACP2 with different structures) to final beta-TCP with increasing aging time was observed. The formation of beta-TCP phase is favored due to the incor...

background: recently, tissue engineering has developed approaches for repair and restoration of damaged skeletal system based on different scaffolds and cells. this study evaluated the ability of differentiated osteoblasts from adipose‑derived stem cells (adscs) seeded into hydroxyapatite/ tricalcium phosphate (ha‑tcp) to repair bone. methods: in this study, adscs of 6 canines were seeded in ha...

The present work investigates the crystallization and phase evolution of amorphous calcium phosphate (ACP) partially substituted with smaller (Mg2+, Zn2+) larger (Sr2+, Ba2+) divalent ions in range from 1 to 10 mol % (M/P = 1.5:1). It has been demonstrated that ACP tricalcium (TCP) subsequent transformations between TCP polymorphs strongly depend on nature concentration substituents matrix. Two...

The aim of this study is to produce highly dense Si3N4 based composites with good mechanical properties and bioactivity. ceramics without using sintering aids, Si3N4-HA Si3N4-HA-GNP have been produced by spark plasma (SPS) at temperatures 1525–1550°C. effect reinforcement type content on the densification behavior, phase analysis, microstructural development, properties, in-vitro bioactivity be...

The purpose of this study was to develop an alpha-tricalcium phosphate (alpha-TCP) cement which transforms to hydroxyapatite (HAP) in a relatively short period. We used calcium and phosphate solutions as the liquid phase for the alpha-TCP cement. The alpha-TCP powder was first mixed with CaCl2 solution, and then mixed with NaH2PO4 or Na2HPO3 solution for a total powder/liquid ratio of 1.8. The ...

Phosphate solublization activity of Bacillus subtilis in different carbon and nitrogen sources with insoluble form of phosphate sources like tricalcium phosphate and rock phosphate were studied. TCP solubilization with different carbon sources irrespective of incubation period can be related in the following order: glucose, fructose, arabinose, mannose, sucrose, lactose, and sorbitol. The pH dr...