background: fenugreek (trigonella foenum - graecum l.) is an annual medicinal plant belongs to the legume family and has anti-diabetic, anti-fertility, anticancer, anti-microbial, anti-parasitic and hypocholesterolaemic effects. objective: evaluation of growth and trigonelline /mucilage content in fenugreek under application of plant growth regulators (pgr). methods: the experiment was conducte...

Several compounds have been described as metabolites of nicotinic acid and nicotinamide in mammals. These are nicotinic acid (I), nicotinamide (2)) nicotinuric acid (2)) trigonelline (2)) W-methylnicotinamide (NMN) (3-6)) and 1-methyl-3-carboxylamide-6-pyridone (7, 8). According to the observations of various workers mammals may be divided into two groups in so far as the metabolism of nicotini...

Background: Trigonella foenum-graecum L. commonly known as fenugreek is a rich source of important medicinal metabolite, i.e. trigonelline. Objective: In this study, hairy roots culture as a novel method for trigonelline production was evaluated. Methods: For optimizing the hairy roots culture of Trigonella foenum-graecum, three strains of Agrobacterium rhyzogenes (ATCC15834, MSU440 and K...

Background: Fenugreek (Trigonella foenum - graecum L.) is an annual medicinal plant belongs to the legume family and has anti-diabetic, anti-fertility, anticancer, anti-microbial, anti-parasitic and hypocholesterolaemic effects. Objective: Evaluation of growth and trigonelline /mucilage content in fenugreek under application of plant growth regulators (PGR). Methods: The experiment was conduc...

BACKGROUND Triiodothyronine (T3) and thyroxine (T4) as the main secretion products of the thyroid affect nearly every human tissue and are involved in a broad range of processes ranging from energy expenditure and lipid metabolism to glucose homeostasis. Metabolomics studies outside the focus of clinical manifest thyroid diseases are rare. The aim of the present investigation was to analyze the...

as: Hama e Associa Abstract This study was designed to evaluate effect of trigonelline and ethanol extract of Iraqi Fenugreek seeds on oxidative stress in alloxan diabetic rabbits. Oral dose of (10 mg/12 h) isolated trigonelline or (7.7 ml/12 h) of ethanol extract of Iraqi Fenugreek seeds was administered to the rabbits for four weeks. Plasma malondialdehyde (MDA) and glutathione (GSH), as oxid...

background: trigonella foenum-graecum l. commonly known as fenugreek is a rich source of important medicinal metabolite, i.e. trigonelline. objective: in this study, hairy roots culture as a novel method for trigonelline production was evaluated. methods: for optimizing the hairy roots culture of trigonella foenum-graecum, three strains of agrobacterium rhyzogenes (atcc15834, msu440 and k599) v...

Leaf tissue of alfalfa (Medicago sativa L.) was found to contain prolinebetaine, pipecolatebetaine, hydroxyprolinebetaine, and glycinebetaine. As n-butyl esters, these chemical species exhibit molecular cations at mass/charge ratio (m/z) 200, 214, 216, and 174, respectively, when analyzed by fast atom bombardment mass spectrometry. The underivatized betaines exhibit protonated molecular ions at...