Beta-lactamase enzymes (BLs) have become the most worrisome mediators of antimicrobial resistance expressed by gram-negative bacteria (GNB). The multiple families of BLs have in common the ability to hydrolyze the -lactam rings of one or more members of the penicillins, cephalosporins, cephamycins, carbapenems, and monobactams. Extended-spectrum -lactamases (ESBLs) are a subset of BLs that conf...

Beta-lactamase enzymes (BLs) have become the most worrisome mediators of antimicrobial resistance expressed by gram-negative bacteria (GNB). The multiple families of BLs have in common the ability to hydrolyze the -lactam rings of one or more members of the penicillins, cephalosporins, cephamycins, carbapenems, and monobactams. Extended-spectrum -lactamases (ESBLs) are a subset of BLs that conf...

The E test (AB Biodisk, Solna, Sweden), a new approach developed to test antimicrobial susceptibility, was compared with the agar dilution method for seven-drug antibiogram analysis of Neisseria meningitidis isolates. The overall E-test quantitative accuracy (+/- 1 log2 dilution) was 93% compared with that of agar dilution testing. The E test was then used to perform the susceptibility tests on...

A 32-year-old African American woman with human immunodeficiency virus 1 (HIV-1) and a 3-year history of extensive facial molluscum contagiosum (MCV) presented to the dermatology clinic for treatment. The patient had been treated with multiple therapies, including liquid nitrogen, topical 0.05% liquid tretinoin, and 0.5% topical podofilox, with no improvement and some secondary irritation to th...

AIM To investigate the change of the antibiotic resistance profiles of the nosocomial Acinetobacter baumannii isolates in intensive care units (ICUs) between the years 2008 and 2011. MATERIALS AND METHODS A. baumannii isolates that were responsible for ICU-acquired nosocomial infections between 2008 and 2011 were included in the study. The susceptibility rates of the antibiotics that are main...

Recently, methicillin-resistant Staphylococcus aureus (MRSA) has emerged as a cause of community-acquired (CA) infections among patients without established risk factors for MRSA. CA-MRSA strains mainly cause mild skin and soft tissue infections in otherwise healthy children and young adults, but can also cause severe necrotizing fasciitis and pneumonia. In contrast to nosocomial MRSA, CA-MRSA ...

Apatient receivingwarfarin for atrial fibrillation experiences worsening of her chronic obstructive pulmonarydiseasewith purulent sputum. You want to start an antibiotic. Her international normalized ratio (INR) has been rock stable at 2.5. Shouldyouadjust thedoseof warfarin? Would the answer be different if she was just ill andyouwerenotgoing touse an antibiotic? Does it depend on the antibiot...

Methicillin-resistant Staphylococcus aureus (MRSA) is a global public health problem, associated with considerable morbidity and mortality. The MRSA infections can be hospitalor community-acquired. Hospital-associated MRSA (HA-MRSA) characteristically colonizes or infects hospitalized individuals with predisposing risk factors, usually harbours SCCmec type I, II or III, and is multi-drug resist...

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. One of the most devastating complications that can occur following a penile prosthesis is infectious in nature (1,2). Consequently, both proper patient selection and risk management are essential for prosthetic surgeons. In a recent paper by Palma-Zamora et al. (1) published in the current issue of Translational Andro...

Vaginal colonisation with E. coli appears to be an important prerequisite for the development of UTI. Whereas colonisation with P fimbriated strains has been clearly shown to predispose to pyelonephritis, virulence factors which predispose to cystitis have not been so clearly identified. Several host genetic and behavioural factors have been found to be associated with increased colonisation wi...