A novel three-dimensional metal-organic framework (MOF), Ag4(tpt)4{δ-[Mo8O26]}·1.5H2O (A) (tpt = 2,4,6-tris(4-pyridyl)-1,3,5-triazine), possesses a ths-type topology with the hinge deformation mode. The single-crystal X-ray diffraction study shows that A and the dehydrated phase Ag4(tpt)4{δ-[Mo8O26]} (B) display distinct anisotropic thermal expansion with expansion in the b direction but contra...

its comparative rarity may be indicated by the fact that in a review of the literature for the ensuing fifty-two years (Stieve 1916) only thirty-nine cases were collected. Lapidus, Guidotti and Coletti (1943) discovered six cases while examining 75,000 men drafted to an American Army centre. These workers quoted a statement by Dr M. Pomeranz. radiologist of the Hospital for Joint Diseases in Ne...

A case of a mentally retarded male patient with associated physical abnormalities resembling the multiple exostoses-mental retardation syndrome (MEMR, Langer-Giedion or Ale-Calo syndrome) is reported. The patient represents one of the most severe examples of this condition; he also has a triphalangeal thumb with double distal phalanges, a feature not reported previously.

Commonly affected anomalies are anorectal malformations (imperforate anus, anteriorly placed anus, anal stenosis), hand malformations (preaxial polydactyly, triphalangeal thumb, bifid thumb), external ear malformations (microtia, “satyr” or “lop” ear, preauricular tag or pits) with sensorineural hearing loss, and renal malformations. In addition, intellectual disability, learning problems, and ...

Triphalangeal thumb (TPT) is a rare congenital disorder characterised by a long, finger-like thumb with three phalanges instead of two. It can occur as an isolated defect, in association with other abnormalities of the hands and feet, or as a part of a syndrome. Sporadic cases have been described, but it is usually inherited as an autosomal dominant trait. In order to examine skeletal morpholog...

Triphalangeal thumb‑polysyndactyly syndrome (TPT‑PS) is an autosomal dominant disorder with complete penetrance and a variable expression consisting of opposable triphalangeal thumbs, duplication of the distal thumb phalanx, pre‑axial polydactyly and duplication of the big toes (hallux). The causative gene of TPT‑PS has been mapped to 7q36.3. Sonic hedgehog (SHH) expressed in the zone of polari...