This paper analyzes the changing relationship of tacit to codified knowledge over three industrial revolutions. Knowledge is increasingly “polyvalent” as theoretical, practical and interdisciplinary implications form a common center of gravity. The changing nature of knowledge drives the institutional spheres of university and industry together in advanced industrial societies and developing co...

Aims—Insulin-like growth factor type I (IGF-I) antisense cellular gene therapy of tumours is based on the following data: rat glioma or hepatoma cells transfected with the vector encoding IGF-I antisense cDNA lose their tumorigenicity and induce a tumour specific immune response involving CD8 T cells. Recently, using the IGF-I triple helix approach in studies of tumorigenicity, major histocompa...

INDEX General remarks About the content of the papers The convergence of the problems that are currently facing the research process in general and the universities in particular Is the Triple Helix a “complete” concept? The role of the users in the Triple Helix or the problem of the setting of the research agenda by social demands The role of public policies The new role of the university The ...

A Triple Helix (TH) of biand trilateral relations among universities, industries, and governments can be considered as an ecosystem in which uncertainty can be reduced auto-catalytically. The correlations among the distributions of relations span a vector space in which two vectors (P and Q) represent “sending” and “receiving,” respectively. These vectors can also be understood in terms of the ...

-1 Programmed ribosomal frameshifting (PRF) in synthesizing the gag-pro precursor polyprotein of Simian retrovirus type-1 (SRV-1) is stimulated by a classical H-type pseudoknot which forms an extended triple helix involving base-base and base-sugar interactions between loop and stem nucleotides. Recently, we showed that mutation of bases involved in triple helix formation affected frameshifting...

Abstract As part of contemporary Triple Helix operations, universities are more and frequently asked to collaborate with other social actors generate knowledge that supports their innovation development activities foster economic growth. In addition research education tasks, developing formal informal collaborations industrial organizations fulfill the third mission societal effectiveness recei...

Abstract Since the emergence of Triple Helix, expansions to Quadruple, Quintuple, N-tuple helices, and models decomposing higher-order helices into multiple interrelated triple or two-layer have been proposed. Albeit presenting alternative conceptual frameworks these different Helix seem unsuited address internal boundaries institutional spheres university, industry, government. Addressing this...