Experiments were designed to examine the release of testosterone through polydimethylsiloxane (PDS) capsules in vitro and in situ and to test the efficacy of PDS capsules in maintaining testosterone in the peripheral circulation of castrate male rabbits for several months. The results demonstrate that (1) tritiated testosterone passed through PDS capsules suspended in water, (2) the tritiated m...

A sample of tritiated lanthanum nickel aluminum alloy (LaNi4.25Al0.75 or LANA.75) similar to that used at the Savannah River Site Tritium Facilities was analyzed to estimate the particle size distribution of this metal tritide powder and the rate at which this material dissolves in the human respiratory tract after it is inhaled. This information is used to calculate the committed effective dos...

SCHLOERB, PAUL R. Total body water distribution of weatinine and urea in nephrectomized dogs. Am. J. Physiol. I 99(4) : 66 1-665. 196o.-It was the purpose of this st.udy to measure and to compare the volumes of distribution of creatinine, urea and tritiated water in nephrectomized dogs. After bilateral nephrectomy a solution containing known amounts of these was infused intravenously and at a c...

Recent studies of the fluxes of sodium and chloride across euryhaline teleost fish have shown that acclimation to fresh water involves a sharp reduction in the flux of both ions (Evans, 1967 c, 1969; Motais, 1967; Maetz et al. 1967 a, b; Potts & Evans, 1967; Ports et al. 1967). It has been shown, at least in Fundulus heteroclitus (Potts & Evans, 1967), Tilapia mossambica (Potts et al. 1967), Xi...

Of all the substances used for the estimation in vivo of total body water content, the most attractive are the isotopes of hydrogen, since they enter into all the metabolic processes involving water and have no selective secretion or storage. Deuterium was the first substance used for body water estimation in vivo (Hevesy and Hofer, 1934) and is preferable to tritium because it is not radioacti...