[PDF] [Full Text] [Abstract] , June 16, 2005; 22 (1): 1-7. Physiol Genomics T. E. Gillis, B. Liang, F. Chung and G. F. Tibbits troponin C Increasing mammalian cardiomyocyte contractility with residues identified in trout [PDF] [Full Text] [Abstract] , August 15, 2007; 583 (1): 337-350. J. Physiol. K. L. Kreutziger, T. E. Gillis, J. P. Davis, S. B. Tikunova and M. Regnier activation in rabbi...

OBJECTIVE To determine whether cardiac troponin T increases after electrical cardioversion in patients with atrial fibrillation or atrial flutter. DESIGN Serum creatine kinase (CK), creatine kinase-MB (CKMB), and cardiac troponin T were measured before, 24 hours, and 48 hours after cardioversion in 15 patients with atrial fibrillation or atrial flutter. RESULTS 12 of the 15 patients (80%) w...

of evidence The High Sensitivity Cardiac Troponin T Assay for Rapid Rule-out of Acute Myocardial Infarction trial was a prospective, multicentre, diagnostic study done at 12 sites, across three continents to validate the diagnostic accuracy of the troponin T 0-hour/1-hour algorithm for rule-in and rule-out of acute myocardial infarction. Current troponin assays for the diagnosis of myocardial i...

BACKGROUND Different cardiac troponin I (cTnI) assays give different results. Only 1 manufacturer has marketed troponin T (cTnT) assays. Therefore, cTnT often is preferred for detection of myocardial infarction in human patients. Studies of cTnT in horses are limited. OBJECTIVES To compare a cTnI and a high-sensitive cTnT assay (hs-cTnT) in horses. ANIMALS Cardiac troponin I and cTnT were d...

BACKGROUND The purpose of this observational study was to test the diagnostic performance of the Elecsys® troponin T high-sensitive system combined with copeptin measurement for early exclusion of acute myocardial infarction (MI) in clinical practice. METHODS Troponin T high-sensitive (diagnostic cutoff: <14 pg/mL) and copeptin (diagnostic cutoff: <14 pmol/L) levels were determined at admissi...

OBJECTIVE To determine whether a single blood test for the measurement of C reactive protein, or troponin I or T concentrations could be used to stratify patients with intractable unstable angina awaiting transfer for coronary angiography by correlating these values with coronary anatomy and transient myocardial ischaemia. DESIGN Prospective study. SETTING Tertiary cardiac unit. PATIENTS ...

We present a case where the laboratory was asked to investigate suspected interference in our troponin T assay. The patient 29-year-old male with schizophrenia on long term clozapine. Hs-Troponin (Roche), performed routine monitoring chronically elevated between 40 100 ng/L (RI <14 ng/L), multiple cardiac investigations being normal. Creatine kinase similarly 400 700 U/L <250 U/L) over same tim...

Severina ME, et al. Troponin I is released in bloodstream of patients with acute myocardial infarction not in free form but as complex. Clin Chem 1997;43:1379–85. 12. Giuliani I, Bertinchant J-P, Granier C, Laprade M, Chocron S, Toubin G, et al. Determination of cardiac troponin I forms in the blood of patients with acute myocardial infarction and patients receiving crystalloid or cold blood ca...

With the introduction of high-sensitive assays, cardiac troponins became potential biomarkers for risk stratification and prognostic medicine. Observational studies have reported an inverse association between physical activity and basal cardiac troponin levels. However, causality has never been demonstrated. This study investigated whether basal cardiac troponin concentrations are receptive to...

OBJECTIVE To assess the diagnostic efficiency of the third generation cardiac troponin T assay in routine clinical practice. DESIGN Prospective observational study of unselected consecutive admissions. SETTING Multicentre study in 43 teaching and non-teaching hospitals in 13 countries. SUBJECTS 1105 hospital admissions, median age 67 years (range 15-96 years, 63.7% male) with suspected ac...