Tuberculosis (TB) is a more prevalent granulomatos bacterial infection, which remains the world’s second most common cause of death due to infections of Mycobacterium tuberculosis (M.Tuberculosis). A number of characteristics of mycobacterium makes there disease chronic and necessitate prolonged treatment. The emergence of multi-drug-resistance (MDR) stains of M.Tuberculosis makes its necessary...

BACKGROUND The objective of this study was to report the use of multi-targeted polymerase chain reaction (PCR) in the diagnosis of presumed tubercular uveitis. Multi-targeted PCR using three targets specific for Mycobacterium tuberculosis, i.e., IS6110, MPB64, and protein b, was performed on intraocular fluid samples of 25 subjects. Nine had presumed tubercular uveitis, six had intraocular infl...

Tubercular involvement of small bones is a rare clinical condition. Often, the disease associated with pulmonary involvement. Isolated cases spina ventosa in adults no seeding or any history tuberculosis trauma are relatively infrequent occurrences. We report case 22-year-old immunocompetent Indian female who presented complaints swollen right index finger. A detailed workup supported by radiog...

Musculoskeletal tuberculosis accounts for 1-2% of all types of tuberculosis. Tubercular abscess of the chest wall accounts for 1-5% of all cases of musculoskeletal tuberculosis. Herein, we report a case of tubercular abscess of the chest wall. The occurrence of caries rib and cold abscess of the chest wall with concomitant pulmonary tuberculosis, and tubercular lymphadenitis of neck and mediast...

BACKGROUND The emergence of drug-resistant strains of Mycobacterium tuberculosis has become a global public health problem. Polyherbal medicines offer great hope for developing alternative drugs for the treatment of tuberculosis. OBJECTIVE To evaluate the anti-tubercular activity of polyherbal medicines used for the treatment of tuberculosis. METHODS The remedies were screened against Mycob...

Tuberculosis is one of the leading contagious diseases, caused by Mycobacterium tuberculosis. Despite improvements in anti-tubercular agents, it remains one of the most prevalent infectious diseases worldwide, responsible for a total of 1.6 million deaths annually. The emergence of multidrug resistant strains highlighted the need of discovering novel drug targets for the development of anti-tub...