There unquestionably has been a marked improvement of late with respect to classifying cases of leprosy, because of the fairly general adoption of the classification recommended by the Memorial Conference. However, a serious impediment to reasonably uniform practice in this matter still remains in the problem of placing those cases whose principal skin lesions are infiltrated, active leprides o...

Deep pain upon percussion of lesions over bone in tuberculoid leprosy, in spite of superficial sensory impairment, has been described as the "Tap Sign" (TS). This study was conducted to identify possible causes for this phenomenon and to determine the sensitivity and specificity of this sign in leprosy patients with lesions overlying bone. In 37/53 patients with lesions over bone, the sensitivi...

Lepromatous leprosy is a sys temic disorder. In many cases there is extensive involvemen,t not only of the reticuloendothelial system, but also of other organs. Intimal cells of blood vessels may be almost bursting with leprosy bacilli. Liver changes in lepromatous leprosy are well known. They consist chiefl y of foam-cell granulomas, with or without acid-fas t bacilli, in the portal ti ssues a...

I. HISTORICAL II. IMPORTANCE OF THE TUBERCULOID FORM III. THE SOUTH AMERICAN CLASSIFICATION IV. COMMENTS ON SOUTH AMERICAN CLASSIFICATION 1. The question of transformation from the tuberculoid to the lepromatous type. 2. The difficulty of clinically differ entiating the neural cases. V. THE NATURAL COURSE OF THE INFECTION IN LEPROSY VI. A FOURTH FUNDAME NTAL TYPE OF LEPROSY VII. A PROPOSED MODI...

Regional differences in leprosy constitute major difficulties in our common understanding of the disease. The incidence of lepra fever, tuberculoid reaction, .ulcerative tuberculoid leprosy, leprotic affections of the eye, peripheral nerve involvement and leprotic alopecia varies so markedly as to make the commonplaces of one area the rarities of another. Again the relative proportion of tuberc...