BACKGROUND Exercise training programs have emerged as a useful therapeutic regimen for the management of type 2 diabetes mellitus (T2DM). Majority of the Western studies highlighted the effective role of exercise in T2DM. Therefore, the main aim was to focus on the extent, type of exercise and its clinical significance in T2DM in order to educate the clinicians from developing countries, especi...

Type 2 diabetes (T2DM) is characterized by insulin resistance and beta cell dysfunction. Recent evidence has emerged that beta cell dysfunction is a common pathogenetic feature of both type 1 and type 2 diabetes, and T2DM never develops without beta cell dysfunction. Therefore, treatment of T2DM should aim to restore beta cell function. Although the treatment of T2DM has greatly improved over t...

The incidence and prevalence of type 2 diabetes mellitus (T2DM) are increasing worldwide in the pediatric population. The increase has been attributed to obesity, lack of physical activity, improper diet, and family medical history. Type 2 diabetes mellitus has serious complications for children, including cardiovascular problems, dyslipidemia, hypertension, nonalcoholic fatty liver disease, pa...

Type 2 Diabetes mellitus (T2DM) is a complex and multifactorial metabolic disorder, caused by an interplay of genetic variations, unhealthy lifestyles environmental factors. For many years, pharmacogenomics contributed to great step towards precision medicine (1). The evidences from have revolutionized our understanding the role variations in T2DM pathogenesis therapeutic response antidiabetic ...

The discovery of diabetes mellitus (simplified as “diabetes”) could be traced back to 1500 B.C. The first detailed description appeared in 1800, but in the last few decades, the prevalence of diabetes increases dramatically. Till present, according to WHO’s report, 247 million people worldwide have been diagonized Diabetes, among which 3.47 million died from diabetes. Thus, WHO projects that di...

J Diabetes Metab Diabetic Neuropathy ISSN:2155-6156 JDM, an open access journal Type 2 Diabetes Mellitus (T2DM) is a systemic metabolic disorder associated with serious and often life-threatening complications. Diabetic neuropathy is a common complication affecting more than half of T2DM patients [1]. Neurological abnormalities affecting the distal lower extremities are known to appear in the e...

diabetes mellitus is a multifactorial disease. it has recently been shown that an insertion (i)/deletion (d) polymorphism exists in the angiotensin-converting enzyme (ace) gene that can affect the serum ace level. there are three genotypes: dd, di, and ii, with the ace level being highest in dd, intermediate in di, and lowest in ii. in the present investigation, 170 patients with type 2 diabete...

background: diabetes mellitus is a serious public health problem worldwide and particularly in developing countries. in algeria, this metabolic disorder occurs with a wide variety or atypical forms that linked to multiple risk factors including local habits and traditions. this study aimed to determine the impact of risk factors (metabolic syndrome, social, cultural, physical activity, family h...