AIM: To identify pathologic features associated with this “ulcerative colitis (UC)-like” subgroup of Crohn’s

Inflammatory bowel diseases (IBD) are chronic inflammatory disorders, including Crohns’ disease (CD) and ulcerative colitis (UC), both characterized by a clinical relapsing course an immune-mediated pathogenesis [...]

background: inflammatory bowel disease, an autoimmune disease, has two clinical manifestations including crohn’s disease and ulcerative colitis (uc). il-17 has been the target of intensive research in autoimmune diseases. the influence of toll like receptor 4 (tlr-4) gene polymorphisms on il-17 production has also been revealed in uc patients and tissue inflammation in mice. objectives: to inve...

background the incidence of inflammatory bowel disease (ibd) varies among different societies. the aim of this study is to determine the incidence rate of ibd in kerman, a city in southeast iran. methods all medical records that indicated a new diagnosis of ulcerative colitis (uc) or crohn`s disease (cd) were retrieved from the gastrointestinal endoscopy and pathology departments of 12 centers ...

BACKGROUND The incidence of ulcerative colitis (UC) is rising in populations with western-style diet, rich in fat and protein, and low in fruits and vegetables. In the present study, we aimed to evaluate the association between dietary protein intakes and the risk of developing incident UC. METHODS Sixty two cases of UC and 124 controls were studied using country-specific food frequency quest...

Ulcerative colitis (UC) and Crohn’s disease (CD) are the two common forms of inflammatory bowel disease (IBD). They share similar clinical and demographic features as well as harbor key differences in tissue damage and prognosis. Previous studies indicated that they contributed to the increased rick to Colorectal cancer (CRC). However, whether UC and CD share inflammatory signatures still remai...

The primary goals of therapy in the treatment of ulcerative colitis (UC) are to induce remission of patient symptoms as rapidly as possible and maintain remission on a long-term basis. New formulations of mesalazine and corticosteroids show promise in improving compliance and efficacy. There is consistent evidence for the role of cyclosporine in severe UC and expanding evidence for thiopurines ...

Although extraintestinal manifestations of inflammatory bowel diseases are not uncommon, few reports have described concurrent idiopathic thrombocytopenic purpura (ITP). Spontaneous pneumomediastinum is also a rare complication of ulcerative colitis (UC). This report describes the case of a 14-year-old boy who experienced recurrent ulcerative colitis 3 months after temporary improvement followi...

the association of takayasu arthritis (ta) and inflammatory bowel disease is rare. early diagnosis and treatment may influence patient survival. this report describes a 35-year-old woman who had been treated for ulcerative colitis (uc) that manifested with weight loss, upper limb cluadication and vertigo. the diagnosis of ta was made according to the american college of rheumatology criteria. t...

Inflammatory bowel diseases, particularly ulcerative colitis (UC) and lymphocytic colitis (LC), affect many people. The role of melatonin in the pathogenesis of UC is precisely determined, whereas in LC it remains unknown. The aim of this study was to compare the expression of the melatonin-synthesizing enzymes tryptophan hydroxylase (TPH1), arylalkylamine-N-acetyltransferase (AANAT), and N-ace...