This work describes the application of ultrasound-assisted matrix solid-phase dispersion as an extraction and sample preparation approach for aflatoxins (B1, B2, G1 and G2) and subsequent determination of them by high-performance liquid chromatography-fluorescence detection. A Box-Behnken design in combination with response surface methodology was used to determine the affecting parameters on t...

We demonstrate that dispersion of single walled carbon nanotubes (SWNTs) by ultrasonication with phospholipid-polyethylene glycol (PL-PEG) fragments it, thus interfering with its ability to block nonspecific uptake by cells. However, unfragmented PL-PEG promoted specific cellular uptake of targeted SWNTs to two distinct classes of receptors expressed by cancer cells. Since fragmentation is a li...

Voriconazole is a second-generation antifungal agent with excellent broad spectrum of antifungal activity commercially available for oral and intravenous administration. Systemic administration of voriconazole is associated with side effects including visual and hepatic abnormalities. This study assessed the feasibility of using solid lipid nanoparticles for ocular delivery of voriconazole adop...

the purpose of this study is to produce an oil-in-water nano-emulsion by ultrasonication. casein combined with inulin used as continuous phase, while dispersed phase consisted of fish oil. the size of the nano-emulsion and the ph of nano-emulsion were characterized. ultrasound has been used for preparing emulsion by 24 khz intensity for 120 seconds. prepared nano-emulsion was investigated by pa...

The solubility of acid soluble soy protein (ASSP) is poor in the pH range of 4-7. ASSP-dextran conjugates were prepared through the Maillard reaction to increase the solubility and/or dispersibility of ASSP. By using the conjugates and ultrasonication emulsification, stable oil-in-water emulsions with submicrometer-sized droplets were obtained. The factors, such as ASSP conjugation degree, that...

Plant extracts having an inhibitory effect on aging may be a good choice for cosmetic applications because of their natural origin. The extraction of bioactive compounds from plants is one of the most critical steps in the commercial development of natural products. Therefore rapid and efficient phytochemical extraction methods are essential. The present study involves the use of microwave and ...

The aim of this research was to investigate the effect of the duration of ultrasonication energy on the physicochemical characteristics of the nano-sized particulate drug delivery systems. For this purpose, meloxicam-loaded vitamin E d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS)-emulsified poly (D,L-lactide-co-glycolide) (PLGA) nanoparticles were designed by using ultrasonication-sol...

• Dairy manure and digestate were assessed on their bioaccessibility complexity. Ultrasonication of 29 days old increased sCOD by 55% BMP 32%. 43 did not increase significantly. The improved after ultrasonication.

Purpose: To prepare and optimize esomeprazole nanosuspension to enhance drug dissolution rate. Methods: Esomeprazole nanosuspensions were prepared by evaporative precipitation-ultrasonication method using F68 (Poloxamer 188) and F127 (Poloxamer 407) as stabilizers. Formulation and process variables (concentration of stabilizers and drug, power input and duration of ultrasonication) affecting th...

Solubilisation of myofibrillar proteins in physiological or low ionic strength solutions is essential for their utilisation as supplementary protein food. In order to achieve low ionic strength solubility, ultrasonication as a physical force has been introduced as an effective method to shift the solubility range of myofibrillar proteins from high to low ionic medium. In this study, change in t...