BACKGROUND An umbilical metastatic lesion is called 'Sister Mary Joseph's nodule'. It is an uncommon clinical or radiographic finding, and it is rare as the first sign of a malignant disease. CASE PRESENTATION We report three cases of Sister Mary Joseph's nodule. In the three cases presented, the primary tumor was an adenocarcinona of the sigmoid colon, a carcinoma of the bladder, and an aden...

The finding of umbilical metastasis has historically been called a "Sister Mary Joseph Nodule". A few case reports of lymphoma presenting in this manner have been documented. We report a case of relapsed mantle cell lymphoma (MCL) presenting as a Sister Mary Joseph's nodule. Although the few reports of lymphoma exhibiting umbilical metastasis suggest that patients may still expect a reasonable ...

Sister Mary Joseph's nodule is an important physical sign. It usually represents umbilical metastasis of intra abdominal malignancy. Its association with intra abdominal desmoplastic small round cell tumour is extremely rare. We describe a rare case of sister Mary Joseph's nodule associated with desmoplastic small round cell tumour. We conclude that differential diagnosis of Sister Mary Joseph'...

Umbilical metastasis is one of the main characteristic signs of extensive neoplastic disease and is universally referred to as Sister Mary Joseph's nodule. It indicates neoplasm of inner organs mostly located in the gastrointestinal tract or the pelvis. However, in approximately 15-30% the primary tumor remains occult. In most cases, Sister Mary Joseph's nodule appears as an early and sometimes...

Background: Sister Mary Joseph Nodule (SMJN) is a rare metastatic umbilical nodule with primary tumor genital or gastrointestinal sites. Pancreas location for metastases. Pancreatic adenocarcinoma associated SMJN usually arise from the body and tail of pancreas. We report case SMJ nodule’s as cutaneous manifestation pancreatic head cancer. Case Report: A 59-year-old man, presented epigastric, b...

Sister Mary Joseph nodule is the umbilical metastasis detected in cancer patients. There are various theories on the formation of umbilical metastases; however, the primary focus is often placed either in the abdomen or pelvis. Its prognosis is dismal. In this article, we aimed to present a 44-year-old male patient who presented with obstruction and was subsequently diagnosed with colorectal ca...

The most common somatic type malignancy arising in patients with testicular germ cell tumors (GCTs) is sarcoma. Development of carcinomas, especially squamous cell carcinoma is an extremely rare event. Most cases of metastatic umbilical nodules (Sister Mary Joseph nodule) develop from adenocarcinomas. Fifteen percent of such cases have unknown origin; but development from a testicular squamous ...