background: miscarriage is one of the most common pregnancy complications for which various causes have been defined, such as genetic factors, infectious, metabolic, endocrine systemmal function and immune system undesired responses. the early development of embryo occurs in oviduct and uterine tube from which some factors such as growth factors, glyco-proteins and factors those stimulate devel...

one of the major causes of spontaneous abortion before the fourth month of pregnancy is chromosomal abnormalities. we report an unusual case of a familial balanced chromosomal translocation in a consanguineous couple who experienced 4 spontaneous abortions. chromosomal studies were performed on the basis of g-banding technique at high resolution and revealed 46, xx, t (16 6) (p12 q26) and 46, x...

In order to determine outcome of pregnancy with lUI in patients with unexplained recurrent miscarriage whose husbands have low hypo-osmotic swelling test scores, a prospective clinical intervention was performed at a university referral clinic of recurrent abortion. Out of 56 patients whose husbands had abnormal hypo-osmotic swelling tests, 43 patients underwent lUI, from which only 14 pat...

In order to determine outcome of pregnancy with lUI in patients with unexplained recurrent miscarriage whose husbands have low hypo-osmotic swelling test scores, a prospective clinical intervention was performed at a university referral clinic of recurrent abortion. Out of 56 patients whose husbands had abnormal hypo-osmotic swelling tests, 43 patients underwent lUI, from which only 14 pat...

Introduction: One factor known to cause thrombophilia in women with unexplained recurrent spontaneous abortion (RSA) is C677T polymorphism of methylenetetrahydrofolate reductase gene. This study aimed to determine the association between RSA and MTHFR C677T polymorphism in Iranian patients. Methods: In this case-control study, 30 patients with previous history of two or more consecutive unexpla...

Background: To determine the incidence of an abnormal glucose tolerance test in patients with recurrent spontaneous abortion and whether metformin would safely reduce the rate of first trimester spontaneous abortions in patients without polycystic ovary syndrome (PCOS) as well as with PCOS and an abnormal glucose tolerance test. Materials and Methods: Patients with a history of recurrent sponta...

Recurrent miscarriages are characterized as three or more spontaneous abortions in a row before the 20th week. In majority of instances, genetic factors, immunological and endocrine infection, unknown causes most common first trimester abortion. Hormonal therapy, heparin injection, immunotherapy available treatments. this case study, patient had during trimester. Because all tests came out norm...

Background: Recurrent spontaneous abortion (RSA) is usually defined as three or more consecutive pregnancy losses before 20th week of gestation. Although different factors are considered as etiology of RSA but in some cases, despite of extensive work up, the cause of RSA remains unknown which called unexplained RSA. Immunological factors are suggested as etiological factors of unexplained RSA. ...