نتایج جستجو برای: urea cycle disorders

تعداد نتایج: 967162  

2013
Christopher Perrone Monica Makhija Ann Mitchell

Urea cycle disorders are inherited deficiencies of the enzymes involved in the cellular excretion of excess ammonia produced during protein metabolism. Hyperammonemia associated with these disorders is usually manifested by decreased level of consciousness, irritability, seizures, vomiting, and poor feeding. Although the majority of recognized patients are children, a delayed presentation is se...

Journal: :International Journal of Neonatal Screening 2015

Journal: :Molecular Genetics and Metabolism Reports 2017

Journal: :Current oncology 2014
J Lazier S M Lupichuk I Sosova A A Khan

Hyperammonemic encephalopathy (he) is a rare complication of malignancy and chemotherapy. Although the cause of he is unclear, a functional arginine deficiency secondary to increased catabolism has been suggested as a possible mechanism. Either that deficiency or an undetermined metabolite could lead to inhibition of N-acetylglutamate synthase (nags), a urea cycle enzyme, resulting in hyperammo...

Journal: :The Journal of pediatrics 2001
M Summar M Tuchman

In an effort to develop standards for the treatment of patients with urea cycle disorders, a consensus conference was held in Washington, DC, from April 27-29, 2000. Conference participants included physicians, scientists, nurses, dieticians, and a genetic counselor, all experts in their various medical fields in these diseases. Representatives from the Food and Drug Administration and the Nati...

2004
Fernando Scaglia Nicola Brunetti-Pierri Soledad Kleppe Juan Marini Susan Carter Peter Garlick Farook Jahoor William O’Brien Brendan Lee

Urea cycle disorders (UCD) are human conditions caused by the dysregulation of nitrogen transfer from ammonia nitrogen into urea. The biochemistry and the genetics of these disorders were well elucidated. Earlier diagnosis and improved treatments led to an emerging, longer-lived cohort of patients. The natural history of some of these disorders began to point to pathophysiological processes tha...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید