Extraintestinal Escherichia coli (ExPEC), a heterogeneous group of pathogens, encompasses avian, neonatal meningitis, and uropathogenic E. coli strains. While several virulence factors are associated with ExPEC, there is no core set of virulence factors that can be used to definitively differentiate these pathotypes. Here we describe a multiplex of four virulence factor-encoding genes, yfcV, va...

OBJECTIVES The most common uropathogenic Gram negative bacteria are Escherichia coli and Klebsiella pneumoniae. The purpose of this study was to determine the three most frequent bacterial agents causing Urinary Tract Infections (UTI) in patients who referred to Central Laboratory of Dr. Shariati Hospital, during 2 years (January 2006- December 2007). MATERIALS AND METHODS The registered data...

ADHESINS OF UROPATHOGENIC ESCHERICHIA COLI AND THEIR ROLE IN THE PATHOGENESIS OF URINARY TRACT INFECTIONS

An in vitro system was developed to study the migration of uropathogenic Escherichia coli strains. In this system an aqueous agar gel is placed against a solid surface, allowing the bacteria to migrate along the gel/solid surface interface. Bacterial strains as well as solid surfaces were characterized by means of water contact angle and zeta potential measurements. When glass was used as the s...

Urinary tract infections pose a serious health threat with respect to antibiotic resistance and high recurrence rates. While the host robustly responds to bacterial infiltration into the bladder, uropathogenic Escherichia coli can survive the onslaught to persist for months after initially infecting. To accomplish this feat, uropathogenic E. coli forms intracellular bacterial communities, with ...

results we found a high number of pai markers such as pai icft073, pai iicft073, pai i536, pai iv536, pai ii j96 and pai ii536 significantly associated with upec. the pai iv536 was the most detected ones among fecal e. coli isolated from healthy people while pai i536, pai ii536 and pai ij96 were not seen. pcr phylogenetic groups typing revealed that uropathogenic strains were mainly found in b2...