Uterine cancer is a common cause for cancer death in women and there is no effective therapy for metastatic disease. Thus, research is urgently needed to identify new therapeutic agents. We showed previously that all female HMGA1a transgenic mice develop malignant uterine tumors, indicating that HMGA1a causes uterine cancer in vivo. We also demonstrated that HMGA1a up-regulates cyclooxygenase-2...

INTRODUCTION Uterine cancer was the most rapidly increasing malignancy and the second most common gynecologic malignancy in Taiwan. METHODS We analyzed the secular trend of uterine cancer incidence and compare the survival of women with uterine carcinomas and uterine sarcomas in Taiwan. Data on women diagnosed with uterine cancer between 1979 and 2008 were obtained from the Taiwan cancer regi...

SUMMARY The aim of this survey is to measure the knowledge and behavior of married women who attended to the health centers in southern part of Tehran about the cancer of uterine cervix and Pap Smear test. The selection of region 11 from southern part of Tehran and 350 married women in this region based on random sampling technique. The findings and results of this survey showed that: the maj...

OBJECTIVES Little is known about the ethnic differences in disease presentation of uterine cancer in New Zealand women. The objectives of this study were two-fold: (1) to estimate the incidence and mortality of uterine cancer among women in New Zealand and (2) to examine the association of ethnicity and socioeconomic status with tumour stage and grade, at presentation of uterine cancer. METHO...

Endometrial and ovarian cancers are two most common cancers affecting women in their post-menopausal years. To date, there are no simple biochemical tests to detect these cancers at early stages. Our previous study has demonstrated that the activity of total proprotein convertases (PCs) is significantly increased in uterine lavage at all stages of endometrial cancer, suggesting uterine lavage w...

Uterine corpus cancer has increased in prevalence in Korean women over the last decade. Recently, elegant studies have been reported from many institutes. To improve treatment strategies, a review of our own data is warranted. This work will discuss the risks and prognostic factors for uterine corpus cancer, and the radiologic evaluation, prediction of lymph node metastasis, systematic lymphade...

Uterine body cancer (UBC) makes up 7.1% of malignant tumors in women and ranks 6th the structure incidence world after breast cancer, cervical colorectal lung thyroid cancer. In developed countries, it is most common tumor female genital organs. The study included 105 patients with a diagnosis stage I uterine were divided into 2 groups: - main group consists 60 who received preoperative brachyt...

It is well-known that tamoxifen increases the risk of endometrial cancer. Although metastasis to the uterus from breast cancer is uncommon, there have been some case reports on uterine metastasis. If an endometrial abnormality is detected, the differential diagnosis of whether the uterine tumor is metastatic or primary is very important to determine the course of treatment. We herein report a c...

Objective To analyze the events preceding incomplete surgical staging procedures in endometrial cancer patients. Design Retrospective descriptive study Setting Department of Obstetrics & Gynecology, Faculty of Medicine, Chiang Mai University Subjects Thirty patients who were unexpectedly found to have endometrial cancer after undergoing hysterectomy for benign conditions and were referred to Ch...

Synchronous cancer is referred to two or more histological distinct malignancies diagnosed during the same hospital admission. Globally more than 1 million people get colorectal cancer yearly resulting in about 0.5 million deaths. Vulvar cancer is the fourth most common gynecologic cancer (following the corpus uterine cancer, cancer of ovary and cervix) and comprises only 4 percent of malignanc...