To cite: Mestre T, Amaro C, Freitas I. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2014204612 DESCRIPTION The authors report a case of an 11-year-old boy with a congenital lesion on the left leg, initially described as a blue macule which progressed to a verrucous pigmented plaque (figure 1). MRI (figure 2) showed local infiltration of the lower dermis and sub...

Biallelic inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene predisposes human patients to the development of highly vascularized neoplasms in multiple organ systems. We show that zebrafish vhl mutants display a marked increase in blood vessel formation throughout the embryo, starting at 2 days post-fertilization. The most severe neovascularization is observed in distinct areas t...

Epithelioid hemangiosarcoma is a specific variant of hemangiosarcoma that has recently been recognized in domestic animals. These malignant vascular neoplasms histologically resemble, and may be mistaken for, carcinomas. Four epithelioid hemangiosarcomas in the urinary bladders of 4 cows with severe enzootic hematuria are described in the current study. Grossly, the vesicular mucosa of the urin...

The neoplasms of the Parpharyngeal Space (PPS) are rare 0.5%-1% all head and neck tumors [1]. PPS is an inverted cone-shaped region that extends from skull base to hyoid bone. A complex structure called tensor-vascular-styloid fascia, divides into prestyloid poststyloid compartments. can be involved by four different types neoplastic lesions: Primary (benign or malignant), metastatic lymph node...

Haemangioblastomas are true vascular neoplasms which progress inexorably to a catastrophic clinical situation if left untreated. Theyare mostly intramedullary tumours rarely seen in the extramedullary space.An unusual ease with a solitary spinal eord haemangioblastoma loeated purely in the intradural

Hemangiomas are defined as benign neoplasms originating from vascular endothelial tissue. Intraosseous hemangiomas very rare and account for less than 1% of bone tumors. They mostly seen in vertebras, skull bones long bones. jaws. typically asymptomatic grow slowly. In this case report, intraosseous hemangioma was found the mandible patient evaluated clinically, radiologically histopathological...

Perivascular wall tumors (PWTs) are mesenchymal neoplasms in the group of soft tissue sarcomas (STSs) and are defined as neoplasms deriving from mural cells of blood vessels, excluding the endothelial lining. In the present paper, we describe the gross morphology, histopathology and immunoreactivity of a hemangiopericytoma (HP) as a PWT in a dog with recurrence after surgical excision. The mass...

Abstract Thrombotic, vascular, and bleeding complications are the most common causes of morbidity mortality in Philadelphia chromosome–negative myeloproliferative neoplasms (MPNs). In these disorders, circulating red cells, leukocytes, platelets, as well some vascular endothelial each have abnormalities that cell-intrinsic to MPN driver mutations they harbor (eg, JAK2 V617F). When cells activat...

Introduction: Parapharyngeal space (PPS) tumors account for 0.5% of the head and neck neoplasms. Based on the evidence, 80% of these tumors are of a benign nature. Surgical excision is the treatment of choice for this condition. The present study was conducted to propose transoral resection as an efficient way to excise the benign well-defined tumors of the PPS.   Materials and Methods: Thi...

spindle cell neoplasms are defined as neoplasms that consist of spindle-shaped cells in the histopathology. spindle cell neoplasms can affect the oral cavity. in the oral cavity, the origin of the spindle cell neoplasms may be traced to epithelial, mesenchymal and odontogenic components. this article aims to review the spindle cell neoplasms of the oral cavity with emphasis on histopathology.  ...