BACKGROUND Selective serotonin reuptake inhibitors improve cognition in patients with stroke and increase the expression of brain-derived neurotrophic factor (BDNF) in the rat hippocampus. However, the effects of selective serotonin reuptake inhibitors on cognition and serum BDNF levels in patients with vascular dementia are largely unknown. We performed an open-label study to investigate the e...

vascular endothelial growth factor (vegf) is a multifunctional cytokine with distinct functions in angiogenesis, lymphangiogenesis, vascular permeability, and hematopoiesis. vegf is a highly conserved, disulfide-bonded dimeric glycoprotein of 34 to 45 kda produced by several cell types including fibroblasts, neutrophils, endothelial cells, and peripheral blood mononuclear cells, particularly t ...

purpose : to determine the association between retinal vascular diameter and its branching angles with diabetic retinopathy (dr) stages in diabetic patients methods : a descriptive analytic cross-sectional study was conducted in 62 diabetic patients (120 eyes) referred to farabi eye hospital between june 2008 and december 2009. digital fundus photography pictures were imported into photoshop so...

BACKGROUND Though hypertension is a commonly studied risk factor for white matter lesions (WMLs), measures of blood pressure may fluctuate depending on external conditions resulting in measurement error. Indicators of arterial stiffening and reduced elasticity may be more sensitive indicators of risk for WMLs in aging; however the interdependent nature of vascular indicators creates statistical...

Immunoperoxidase staining was carried out using monoclonal antibody against endothelin-1 on renal allograft biopsy specimens from thirty one patients with acute renal transplant rejection: Banff 97 score IA (n = 11), score IB (n = 10) and score IIA (n = 10). As a control 10 biopsy specimens of the kidneys removed because of trauma were used. Endothelin-1 immunostaining was investigated in the r...

BACKGROUND: Surgical teams have not had a routine, reliable measure of patient condition at the end of an operation. We aimed to develop an Apgar score for the field of surgery, an outcomes score that teams could calculate at the end of any general or vascular surgical procedure to accurately grade a patient’s condition and chances of major complications or death. STUDY DESIGN: We derived our s...

A high coronary artery calcification score (CACS) may be associated with mortality in patients undergoing hemodialysis (HD). Recently, effects of iron on vascular smooth muscle cell calcificat...

BACKGROUND AND PURPOSE An ICH patient's risk of harboring an underlying vascular etiology varies according to baseline clinical and NCCT characteristics. Our aim was to develop a practical scoring system to stratify patients with ICH according to their risk of harboring a vascular etiology. MATERIALS AND METHODS Using a data base of 623 patients with ICH evaluated with MDCTA during a 9-year p...