BACKGROUND As both cancer and major orthopaedic surgery are risk factors for venous thromboembolism, patients undergoing lower-extremity oncologic endoprosthetic arthroplasty for neoplastic processes are at substantial risk of the development of symptomatic venous thromboembolism. Therefore, the primary purpose of this study was to determine the incidence of symptomatic venous thromboembolism i...

BACKGROUND There is a known relationship between venous thromboembolism and cancer, but there is no consensus as to how extensive screening for occult cancer should be in cases of venous thromboembolism with no apparent risk factor (idiopathic venous thromboembolism). The aim of this study was to investigate the extent to which limited screening of patients with idiopathic venous thromboembolis...

The routine use of venous thromboembolism prophylaxis in patients undergoing foot and ankle procedures is not well supported in the literature. Multiple studies draw conclusions from heterogeneous populations, and specific studies have small numbers of specific pathologic conditions. Depending on the study, recommendations for and against venous thromboembolism prophylaxis in foot and ankle sur...

STUDY OBJECTIVE To measure the effect of an altered process of care, directed by a computerized reminder system, on rates of symptomatic postoperative venous thromboembolism. DESIGN Comparisons of preintervention and postintervention measurements. SETTING A university-affiliated community hospital in Utah. PATIENTS Two-thousand seventy-seven consecutive patients who underwent major operat...

BACKGROUND Although several genetic determinants (mutations or polymorphisms) have been associated with increased risk of venous thromboembolism, the overall influence of genetic factors on this disease is unknown. METHODS We linked the Danish Twin Registry, which includes twins born 1870-1953, with the Danish National Registry of Patients, comprising all hospitalizations in Denmark since 197...

BACKGROUND Individual risk of recurrent venous thromboembolism affects patient management and might differ between men and women. We did a meta-analysis to assess from available evidence whether men and women have the same risk of recurrent venous thromboembolism after stopping anticoagulant treatment. METHODS Eligible articles were identified by searches of MEDLINE (source PubMed, 1966 to Fe...

BACKGROUND There is evidence demonstrating an association between infection and venous thromboembolism. We recently identified this association in the postoperative setting; however, the temporal relationship between infection and venous thromboembolism is not well defined OBJECTIVE We sought to determine the temporal relationship between venous thromboembolism and postoperative infectious co...

OBJECTIVE To compare the risk of non-fatal venous thromboembolism in women receiving oral contraceptives containing drospirenone with that in women receiving oral contraceptives containing levonorgestrel. DESIGN Nested case-control and cohort study. SETTING The study was based on information from PharMetrics, a United States based company that collects information on claims paid by managed ...

Although the risk of venous thromboembolism is increased among oral contraceptive users compared with nonusers who are not pregnant and not taking hormones, and some data have suggested that use of drospirenone-containing pills has a higher risk of venous thromboembolism, this risk is still very low and is much lower than the risk of venous thromboembolism during pregnancy and the immediate pos...