Background: Venous ulcers are a major problem for patients with chronic venous disease (CVD) such as varicose veins. Its treatment is very complex and requires great care, such that inappropriate responses to various medical and surgical treatment could change this condition. This report aims to provide clinical experiences of Iranian traditional medicine that ...

We investigated the associations between the self-evaluated pain status and two pain biomarker candidates, nerve growth factor and S100A8/A9, in exudate from venous leg ulcer to finally develop an objective pain evaluation method. Patients with venous leg ulcer participated in this cross-sectional observational study conducted between April and October 2014 at two medical facilities. During rou...

In an attempt to clarify the pathophysiology of haemodynamics in legs with venous ulcer we investigated the effect of a single intermittent pneumatic compression treatment on the peripheral resistance of leg arteries and the cutaneous laser Doppler flux in the leg. Eight patients with venous leg ulcers and 10 subjects with healthy legs were investigated. Doppler waveforms of the leg arteries an...

Venous ulcer patients can experience this situation for several years without achieving healing if treatment is inadequate. Evidence-based professional practice generates effective results for patients and services. This research aimed to carry out a systematic review to assess the most effective method to improve venous return and the best topic treatment for these ulcers. Studies were collect...

Venous ulceration is the most severe and debilitating outcome of chronic venous insufficiency in the lower limbs and accounts for 80 percent of lower extremity ulcerations. The morbidity caused by them has a serious impact on the quality of life. Sustained venous hypertension, caused by venous insufficiency leads to venous ulceration. The diagnosis is mainly clinical but needs to be differentia...

Venous ulcer is the most advanced stage of chronic venous insufficiency (CVI). Its prevalence is estimated to be between 1% and 3%. Recent articles have suggested that leg ulcers with reflux in superficial veins can be treated by endovenous laser ablation (EVLA). Endovenous laser ablation of the great and/or short saphenous vein has already become the treatment of choice for varicose vein and c...

BACKGROUND Venous leg ulceration is a common and costly problem that is expected to worsen as the population ages. Current treatment is compression therapy; however, up to 50 % of ulcers remain unhealed after 2 years, and ulcer recurrence is common. New treatments are needed to address those wounds that are more challenging to heal. Targeting the inflammatory processes present in venous ulcers ...

OBJECTIVE To determine the clinical efficacy and local haemodynamic effects of perforating vein surgery in ulcerated limbs with combined deep and perforating vein incompetence. DESIGN Prospective, interventional study. MATERIALS AND METHODS Seven ulcerated limbs with combined primary deep and perforating vein incompetence were studied. Clinical efficacy was determined by ultimate ulcer heal...

OBJECTIVE To evaluate the prognostic factors in uncomplicated venous leg ulcer healing. DESIGN Randomised parallel group controlled trial with subjects stratified by initial ulcer diameter and four months' maximum duration of follow up. SETTING Assessment at Northwick Park Hospital vascular unit with community based treatment. PATIENTS 200 patients with clinical and objective evidence of ...