E tubes coated with silver, which has shown potent broad-spectrum antimicrobial activity in vitro, reduced the incidence of ventilatorassociated pneumonia by 35% in a multicenter study, researchers reported. “This is the first intervention demonstrated to reduce ventilator-associated pneumonia incidence that does not require more effort or supervision from clinicians providing bedside care,” sa...

1. Pneumatikos IA, Dragoumanis CK, Bouros DE: Ventilator-associated pneumonia or endotracheal tube-associated pneumonia? An approach to the pathogenesis and preventive strategies emphasizing the importance of endotracheal tube. ANESTHESIOLOGY 2009; 110:673–80 2. Berra L, Curto F, Li Bassi G, Laquerriere P, Baccarelli A, Kolobow T: Antibacterial-coated tracheal tubes cleaned with the Mucus Shave...

1 . Panchabhai TS , Dangayach NS , Krishnan A , Kothari VM , Karnad DR . Oropharyngeal cleansing with 0.2% chlorhexidine for prevention of nosocomial pneumonia in critically ill patients: an open-label randomized trial with 0.01% potassium permanganate as control . Chest . 2009 ; 135 ( 5 ): 1150 1156 . 2 . Koeman M , van der Ven AJ , Hak E , et al . Oral decontamination with chlorhexidine reduc...

This article is presented in form of a current literature review on bacterial complications the early post-liver transplantation period and promising areas for studying effect flora patients after liver transplantation. The paper describes problem emergence, spread, pathogenesis various complications, as well concepts complication’s impact results ventilatorassociated pneumonia are given. A the...

IN a model of ventilated piglets with healthy lungs, we recently demonstrated a substantial deposition of nebulized amikacin into the distal lung. However, only half of the amount of amikacin available for the lungs was eliminated in the urine; the other half was either fixed in the lungs, eliminated by mucociliary clearance, or distributed in other organs. Consequently, consecutive daily nebul...

M e t h o d s Data sources: MEDLINE, CINAHL, EMBASE/Excerpta Medica, Cochrane Central Register of Clinical Trials, National Research Register, the National Health Service Trusts Clinical Trials Register, Medical Research Council U.K. database, National Health Service Research and Development Health Technology Assessment Programme, and British Heart Foundation database (last search in November 2...

Background: Ventilator-Associated Pneumonia (VAP) is the most common hospital acquired infection in the intensive care unit with high mortality rate. The role of the clinical symptoms for the VAP diagnosis is limited. Procalcitonin (PCT), currently interested biomarkers, plays an important role in the diagnosis and the outcome of the ventilator-associated pneumonia patients. Objective: To evalu...

nosocomial bacterial pneumonia in acute, diffuse lung injury. Chest 1981; 80:254–258 9 Campbell GD. Blinded invasive diagnostic procedures in ventilator-associated pneumonia. Chest 2000; 117:207–211 10 Grossman RF, Fein A. Evidence-based assessment of diagnostic tests for ventilator-associated pneumonia: executive summary. Chest 2000; 117(suppl 4):177S–181S 11 Johanson WG Jr, Pierce AK, Sanford...

BACKGROUND Routine deflation of the endotracheal tube (ETT) cuff of critically ill patients receiving MV is common in Australia and New Zealand. Literature about ventilatorassociated pneumonia (VAP) and antibiotic use rates with different ETT cuff maintenance practices is lacking. OBJECTIVE To determine the impact of a change in ETT cuff maintenance from a minimal leak technique to pressure m...