Isolated traumatic rupture of the ventricular septum following blunt chest trauma is rare. We report the case of a patient who sustained blunt chest trauma in a motor vehicle collision. The isolated ventricular septal defect was not discovered by echocardiography until 12 days after accident. Perventricular closure of the defect was performed with occluder. The patient died from a complication ...

Ventricular septal defect, alone or in combination with other cardiac malformations, is the commonest form of congenital heart disease in man. Morphogenically, the ventricular septum is composed of three parts: (a) the conal septum, (b) the septum of the endocardial cushions, and (c) the muscular septum proper. Consequently, most cono-truncal abnormalities (transposition of the great arteries, ...

OBJECTIVE To investigate the possible electrophysiological background of the greater excitability of concentric and eccentric left ventricular hypertrophy types in relation to the asymmetric type. METHODS 187 patients with essential hypertension, without ishaemic heart disease were divided into three groups with regard to left ventricule type: concentric (relative wall thickness >0.42, interv...

Ventricular septal defect, alone or in combination with other cardiac malformations, is the commonest form of congenital heart disease in man. Morphogenically, the ventricular septum is composed of three parts: (a) the conal septum, (b) the septum of the endocardial cushions, and (c) the muscular septum proper. Consequently, most cono-truncal abnormalities (transposition of the great arteries, ...

Postoperative right ventricular (RV) failure is difficult to treat and develops from functional impairment of the underlying free wall and septum. This report describes the vital importance of the ventricular septum in RV structure /function relationships, demonstrates how the helical ventricular myocardial band model defines spatial geometry of the free wall and septum to provide architectural...

To assess regional contractility in idiopathic hypertrophic subaortic stenosis (IHSS), a primary myopathic disorder with documented hyperdynamic ventricular contractions, systolic wall thickening and velocity of contraction of the septum and left ventricular posterior wall were measured in echocardiograms from 16 patients with IHSS and 16 normal subjects. The average thickening of the normal se...

BACKGROUND Idiopathic premature ventricular contractions (PVCs) and ventricular tachycardias (IVTs) originating from the subtricuspid septum and near the His bundle have been reported. However, little is known about the prevalence, distribution, electrocardiographic characteristics and the efficacy of radiofrequency catheter ablation (RFCA) for the ventricular arrhythmias arising from the right...

The distribution of cardiac muscle cell disorganization in different regions of the left ventricular wall was studied quantitatively in 52 patients with hypertrophic cardiomyopathy. Cellular disorganization in the ventricular septum was both common and extensive (mean area of septal tissue section disorganized, 35 i 4%). Disorganization was also substantial (24 ± 3%) in the left ventricular fre...

The muscular ventricular septum separates the flow of oxygenated and de-oxygenated blood in air-breathing vertebrates. Defects within it, termed muscular ventricular septal defects (VSDs), are common, yet less is known about how they arise than rarer heart defects. Mutations of the cardiac transcription factor NKX2-5 cause cardiac malformations, including muscular VSDs. We describe here a genet...