A cross-hybridizing DNA fragment to Vibrio cholerae toxR was cloned from the nonpathogenic light organ symbiont Vibrio fischeri, and three proteins homologous to V. cholerae ToxR, ToxS, and HtpG were deduced from its DNA sequence. V. fischeri ToxR was found to activate a V. cholerae ToxR-regulated promoter, and an antiserum raised against the amino-terminal domain of V. cholerae ToxR cross-reac...

Vibrio cholerae has been sporadically isolated from rivers in Tucumán, Argentina, since the outbreak in 1991. The aim of this study was to determine the environmental reservoir of the bacterium in these rivers, assessing the presence of Vibrio cholerae non-O1 and O1 (the latter both in its viable culturable and non culturable state) and its relationship to environmental physicochemical variable...

An Elek test for enterotoxin-producing strains of Vibrio cholerae is described. Thirty-five out of 37 strains of classical V. cholerae produced positive reactions, but only 1 of 69 E1 Tor vibrio strains was reactive. Tox(-) mutants of V. cholerae were also unreactive in the Elek test.

This review highlighted the following: (i) pathogenic mechanism of the thermostable direct hemolysin produced by Vibrio parahaemolyticus, especially on its cardiotoxicity, (ii) heat-labile and heat-stable enterotoxins produced by enterotoxigenic Escherichia coli, especially structure-activity relationship of heat-stable enterotoxin, (iii) RNA N-glycosidase activity of Vero toxins (VT1 and VT2) ...

Podophyllotoxin, Deoxypodophyllotoxin and Ursolic Acid as Potential Inhibitors of tcpA, ompW, ctxB Genes in Vibrio cholerae: An in-Silico Study

1. Vibrio parahaemolyticus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185 2. Vibrio vulnificus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 191 3. Vibrio cholerae . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...

4. Dziejman M, Balon E, Boyd D, Fraser CM, Heidelberg JF, Mekalanos JJ. Comparative genomic analysis of Vibrio cholerae: genes that correlate with cholera endemic and pandemic disease. Proc Natl Acad Sci U S A. 2002;99:1556–61. http:// dx.doi.org/10.1073/pnas.042667999 5. Chun J, Grim CJ, Hasan NA, Lee JH, Choi SY, Haley BJ, et al. Comparative genomics reveals mechanism for short-term and long-...

2. Nusrin S, Khan GY, Bhuiyan NA, Ansaruzzaman M, Hossain MA, Safa A, et al. Diverse CTX phages among toxigenic Vibrio cholerae O1 and O139 strains isolated between 1994 and 2002 in an area where cholera is endemic in Bangladesh. J Clin Microbiol. 2004;42:5854–6. DOI: 10.1128/JCM.42.12.5854-5856.2004 3. Nair GB, Faruque SM, Bhuiyan A, Kamruzzman M, Siddique AK, Sack DA. New variants of Vibrio c...

Cholera is an epidemic disease and a real public health problem throughout the world, particularly in West Africa. This study provides comprehensive overview of pathogenicity, epidemiology Vibrio cholerae strains’s antibiotics resistance A literature review was conducted online English using keywords “Cholera”, “Vibrio cholerae” “West Africa”, “Epidemiology”, “Antibiotic resistance”. These were...

The emergence and spread of Vibrio cholerae O1 El Tor variant strains causing severe diarrhea has been witnessed worldwide in recent years. In the state of Odisha, India, the spread of the V. cholerae O1 El Tor variant strains was studied during outbreaks in 2008 and 2009. Analysis of 194 V. cholerae O1 Ogawa strains revealed that V. cholerae O1 El Tor variant strains are spreading gradually th...