5- hydroxyisoquinoline undergoes a smooth reaction with alkyl propiolates in the presence of triphenylphosphine (15 mol%) to produce the corresponding (E)-alkyl 3-(isoquinolin-5-yloxy) acrylate in good yields. When the reaction was performed by 2-methyl 4-hydroxyquinoline and 3-nitro 4-hydroxypyridine, similar aryl vinyl ethers were obtained.

ABSTRACT Ru-catalyzed synthesis of mixed alkyl-alkyl acetals via addition of primary alcohols to allyl ethers has been extended to include long-chain and/or functionalized substrates. The catalytic systems for these reactions were generated from RuCl2(PPh3)3 and [RuCl2(1,5-COD)]x and phosphines [PPh3 or P(p-chlorophenyl)3] or SbPh3. Of particular importance is the almost quantitative eliminatio...

Vinyl triflates can be efficiently converted into the corresponding aryl enol ethers by treatment with a phenol, NaO(t)Bu and a catalyst generated from Pd2dba3 and 2-(di-(t)Bu-phosphino)biphenyl.

Dihydropyrans have been prepared by the cyclisation of easily accessible propargyl vinyl ethers with (TFP)AuCl/AgBF(4) as a catalyst in high yields. These compounds undergo acid-catalysed rearrangement into cyclopentenone derivatives.

A two-component condensation reaction between an electron-poor acetylenic ester and a phenol e ciently provides substituted aryl vinyl ethers in a one-pot reaction in the presence of dipotassium hydrogen phosphate in solvent-free conditions.

A novel class of aryl vinyl ethers 3 and diethyl 3-cyano-3-alkylprop-1-en-2-ylphosphonates 4 has been prepared, respectively, from coupling reaction of diethyl 1-(bromomethyl)-2-cyanovinylphosphonate 2 with phenols and Gilman reagents.

A metal-free, mild and efficient method for the synthesis of 2-methylquinolines was successfully developed by condensation of anilines with vinyl ethers in the presence of catalytic amount of iodine. Modification of both pyridine and benzene moieties was easily achieved by changing only the vinyl ether and aniline. In this reaction, the iodine species was revealed to show dual behavior; molecul...

Sir: We recently reported 1 that cobaloximes and cobalamins reacted with vinyl ethers, in the presence of alcohols, to give aceta Is containing cobalt-carbon cr-bonds. On the basis of these, and earlier 2 experiments, we suggested that the reactions proceeded via the intermediary of a Co(lII)-olefin 7r-complex. Schrauzer, et al.,3 then reported that they were unable to confirm our results and c...