نتایج جستجو برای: viral inactivation of plasma products
تعداد نتایج: 21227279 فیلتر نتایج به سال:
Abstract Background and Objectives The plasma industry started during World War II with the need for Plasma Derived Medicinal Products (PDMP). About 30 major plasma products are now commercially available, the most important of which are albumin, coagulation factors and immunoglobulin. Demand for these products is still growing, and these products have become particularly important not only in ...
BACKGROUND B19 virus (B19V) is a human pathogen frequently present in blood specimens. Transmission of the virus occurs mainly via the respiratory route, but it has also been shown to occur through the administration of contaminated plasma-derived products. Parvoviridae are highly resistant to physicochemical treatments; however, B19V is more vulnerable than the rest of parvoviruses. The molecu...
background and objectives: pathogen reduction technologies are among methods to eliminate transfusion transmitted infections. mirasol method using riboflavin in combination with ultraviolet rays is one of them. the aims of this study were to investigate the effectiveness of mirasol method to inactivate some model pathogens as well as examination of the sensitivity of plasma proteins after treat...
in this study, anion-exchange chromatography was used to purify factor vii and factor ix from prothrombin complex (ppsb), which contains coagulation factors ii, vii, ix and x. for this purpose, deae-sepharose cl-6b gel , pharmacia column xk-26 , high flow rate and two stepwise gradients with phosphate citrate buffer were used. the yield of the two lyophylized products, factor vii and factor ix ...
introduction: the role of different parts of the extended amygdala in metabolic signs of stress is not well understood. in the present study, we decided to evaluate the impact of the shell part of nucleus accumbens (nac) on metabolic disturbance induced by electro foot shock stress using transient inactivation method in the rat. methods: male wistar rats (w: 230-250 g) were canuulated unilater...
Antivenoms are preparations of intact or fragmented (F(ab')2 or Fab) immunoglobulin G (IgG) used in human medicine to treat the severe envenomings resulting from the bites and stings of various animals, such as snakes, spiders, scorpions, or marine animals, or from the contact with poisonous plants. They are obtained by fractionating plasma collected from immunized horses or, less frequently, s...
Introduction: During the production process of vaccines against viral diseases, virus inactivation plays a crucial role. β-Propiolactone (BPL) is a compound that is frequently used for inactivation of viruses and production of the vaccines against viral diseases such as rabies. In this study, the effects of concentration of BPL as well as the duration and temperature of incubation with BPL on ...
Introduction: The role of different parts of the extended amygdala in metabolic signs of stress is not well understood. In the present study, we decided to evaluate the impact of the shell part of nucleus accumbens (NAc) on metabolic disturbance induced by electro foot shock stress using transient inactivation method in the rat. Methods: Male Wistar rats (W: 230-250 g) were canuulated un...
the poor orientation of the restaurants toward the information technology has yet many unsolved issues in regards to the customers. one of these problems which lead the appeal list of later, and have a negative impact on the prestige of the restaurant is the case when the later does not respond on time to the customers’ needs, and which causes their dissatisfaction. this issue is really sensiti...
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