conclusions: this study indicates that rsv is a substantial cause of respiratory tract infection in infants less than 2 years old. rt-pcr offers a rapid method for detection of rsv in hospitalized children with lrti. results: during the study period, 9 children had a positive result for rsv infection. the median age of these patients was 10 months. bronchiolitis was the clinical diagnosis of pa...

background upper respiratory tract infections (urti) in children are the most frequent reasons for visiting a family doctor, commonly resulting in inappropriate prescription of antibiotics. in underdeveloped countries, a viral respiratory tract infection may be followed by serious complications. more than 200 viral species are associated with respiratory tract diseases in humans and this number...

The following principles of appropriate antibiotic use for adults with nonspecific upper respiratory tract infections apply to immunocompetent adults without complicating comorbid conditions, such as chronic lung or heart disease. 1. The diagnosis of nonspecific upper respiratory tract infection or acute rhinopharyngitis should be used to denote an acute infection that is typically viral in ori...

parapharyngeal abscess is a life-threatening disease. upper respiratory tract infection is the main cause in children. we present a 15-month-old boy admitted to the emergency ward with the chief complaint of difficulty in breathing caused by parapharyngealabscess. his condition deteriorated gradually, and he transferred to the operation theater quickly for abscess drainage and because of the di...

A substantial proportion of hitherto unexplained respiratory tract illnesses is associated with human metapneumovirus (hMPV) infection. This virus also was found in patients with severe acute respiratory syndrome (SARS). To determine the dynamics and associated lesions of hMPV infection, six cynomolgus macaques (Macaca fascicularis) were inoculated with hMPV and examined by pathological and vir...

background: considering that there was not any regional survey in isfahan, iran regarding the epidemiology of acute respiratory tract infections (arti) in different age groups of general population, the aim of this study was to determine the epidemiologic feature of artis in isfahan using multiplex polymerase chain reaction (pcr) method. materials and methods: in this cross-sectional study,pati...

The studies reported here focus on the relation of nitrogen dioxide exposure to susceptibility to viral respiratory infection in a murine model of pneumonia, created by intratracheal inoculation of an endogenous murine pathogen, mouse cytomegalovirus. The purpose of this work is to clarify the potential role of nitrogen dioxide exposure in the pathogenesis of viral infection of the lower respir...

For more than a century, antibody has been used for passive parenteral immunization against viral and bacterial pathogens. This approach has been successful for prevention of viral respiratory infection and has led to testing of intranasal or aerosol delivery of antibody to passively immunize the respiratory tract mucosal surface. Mucosal delivery may be advantageous because it allows the antib...

drug for the prevention of bronchial asthma and allergic rhinitis attacks. DSCG inhibits the release of chemical mediators, including histamine and tumor necrosis factor, from mast cells. While DSCG is known to induce intracellular signaling events associated with physiological and pathological processes, the molecular mechanisms of DSCGinduced signaling have remained unclear. Recent evidence, ...

The emergence and spread of antimicrobial-resistant bacterial, viral, and fungal pathogens for which diminishing treatment options are available is of major global concern. New viral respiratory tract infections with epidemic potential, such as severe acute respiratory syndrome, swine-origin influenza A H1N1, and Middle East respiratory syndrome coronavirus infection, require development of new...