To test the hypothesis that exercise increases central leptin signaling, and thus reduces dietary weight gain in an aged obese model, we assessed the effects of voluntary wheel running (WR) in 23-month-old F344×BN rats fed a 60% high-fat (HF) diet for 3 months. After 2 months on the HF diet, half of the rats were provided access to running wheels for 2 weeks while the other half remained sedent...

Aminothiols such as WR-2721 and its active free thiol WR-1065 have previously been shown to reduce mutations resulting from ionizing radiation in exponentially growing cells. In this study, non-dividing human G0 T-lymphocytes were exposed to the aminothiol radioprotective agent, WR-1065, 30 min before or 3 h after external beam gamma-irradiation and subsequently assessed for survival and mutati...

Objective(s): In heart failure, the heart-to-mediastinum (H/M) ratio of the delayed image and washout rate (WR) are well-known as a powerful cardiac event predictors. H/M ratio quantifies the accumulation rate of MIBG in the myocardium and WR quantifies reduction of meta-iodobenzylguanidine (MIBG) accumulation in the heart from the early planar image to the delayed pla...

Let G = (V,E) be a graph and let f be a function f : E → {0, 1, 2}. An edge x with f(x) = 0 is said to be undefended with respect to f if it is not incident to an edge with positive weight. The function f is a weak edge Roman dominating function (WERDF) if each edge x with f(x) = 0 is incident to an edge y with f(y) > 0 such that the function f ′ : E → {0, 1, 2}, defined by f ′(x) = 1, f ′(y) =...

Tomato is one of the most cultivated vegetables, playing important role in human feed. Due to its characteristics and composition, tomatoes present reduced shelf life, preservative techniques are required. In this study, response surface methodology was used optimize process conditions during osmotic dehydration (OD) tomato slices, through desirability function. Optimization factors were absolu...

The vaccinia virus strain Western Reserve (WR) A34R gene encodes a C-type lectin-like glycoprotein, gp22-24, that is present in the outer membrane of extracellular enveloped virus (EEV) with type II membrane topology (S.A. Duncan and G.L. Smith, J. Virol. 66:1610-1621, 1992). Here we that a WR A34R deletion mutant (WR delta A34R) released 19- to 24-fold more EEV from infected cells than did WR ...

Clarias meladerma Bleeker, 1846 is one of the native species in Indonesia. Aek Silom Lom habitats catfish moma (C. meladerma) located Labuhanbatu district. The study was conducted to analyze long-weight relationship and condition factors that live Lom. Sample collected from October- December 2021. taken by angler. This weight length calculated using linear allometric model (LAM), while factor f...

Wild rice (WR) is a very nutritious grain that has been used to treat diabetes in Chinese medicinal practice. City diet (CD) is based on the diet consumed by Asian area residents in modern society, which is rich in saturated fats, cholesterol and carbohydrates. The present study was aimed at evaluating the effects of replacing white rice and processed wheat starch of CD with WR as the chief sou...

Brown rice (BR) and white rice (WR) produce different glycaemic responses and their consumption may affect the dietary management of obesity. In the present study, the effects of BR and WR on abdominal fat distribution, metabolic parameters and endothelial function were evaluated in subjects with the metabolic syndrome in a randomised cross-over fashion. In study 1, acute postprandial metabolic...

In the search for new potential antihyperlipidemic agents, the present study focuses on the synthesis of novel N-(benzoylphenyl)-5-substituted-1H-indole-2-carboxamides (compounds 8-12, 15, 16, 18) and investigating their antihyperlipidemic activity using Triton WR-1339-induced hyperlipidemic rats as an experimental model. Hyperlipidemia was developed by intraperitoneal injection of Triton WR-13...