Werner syndrome is a premature aging disease caused by the mutation in the WRN gene. The cloning and characterization of the WRN gene and its product allows investigators to study the disease and the human aging process at molecular level. This review summarizes the recent progresses on various aspects of the WRN research including functional analysis of the protein, interactive cloning, comple...

In this paper, we write down the separable Werner state in a two-qubit system as a convex combination of product states explicitly. The Werner state in a two-qubit system has a single real parameter and varies from inseparable state to separable state according to the value of its parameter. The convex combination of product states gives a hidden variable model to the separable Werner state.

introduction urinary tract infection is a common disease in the general population. however, in patients with frequent urinary tract infection, it is important to determine any treatable cause to avoid recurrence. case presentation herlyn-werner-wunderlich syndrome or ohvira syndrome is a very rare congenital anomaly with uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis. ...

Since October 1949 Werner Forssmann was a regular guest of Prof. Dr. Hugo Wilhelm Knipping in the Medical University Clinic of Cologne. Established himself as urologist in Bad Kreuznach, Werner Forssmann had read about the American further development of heart catherization, which was invented by himself. Prof. Wilhelm Bolt, who was one of the medical station doctors of the Cologne Clinic, had ...

Werner syndrome provides a convincing model for aspects of the normal ageing phenotype and may provide a suitable model for therapeutic interventions designed to combat the ageing process. Cultured primary fibroblast cells from Werner syndrome patients provide a powerful model system to study the link between replicative senescence in vitro and in vivo pathophysiology. Genome instability, toget...