PURPOSE This retrospective study was designed to clarify the role of West syndrome in post-callosotomy seizure outcome in patients with Lennox-Gastaut syndrome. METHODS From September 1989 to May 1999, 74 patients diagnosed with Lennox-Gastaut syndrome received anterior corpus callosotomy at Taipei Veterans General Hospital, Taiwan. All patients were followed for more than 4 years after surge...

Wolf-Hirschhorn syndrome (WHS) is a chromosome disorder (4p-syndrome) which is characterized by craniofacial features and epileptic seizures. Here, we report a case of WHS with West syndrome, in whom the seizures were refractory to several antiepileptic drugs but were responsive to the addition of lamotrigine. The patient had epileptic spasms at age seven months. The interictal electroencephalo...

liable mode of treating cases of snake-bite. In investigations regarding the action of drugs of a complex nature, it frequently occurs that the physiological action of the drug, considered as a whole, differs from its isolated constituents. Thus, while opium is narcotic, thebaia, one of its constituents, is purely excitant, and in doses of one grain causes tetanic spasms (Farquharson). The expe...

This paper elaborates on several important outstanding issues in the state-of-art of overvoltage protection selection for modern wind farms. The lack of experience with this still-new technology, together with the inherent complexity of wind farm electrical systems, entails several unresolved issues pertinent to the topic of overvoltage protection, particularly in relation to lightning-initiate...

West Nile virus (WNV) myocarditis has been documented pathologically in birds and mammals but has rarely been reported in human clinical syndromes. We describe myocarditis associated with WNV.

We investigated humoral and cellular immune response to brain tissues in 15 patients with West syndrome, in 9 patients with Lennox-Gastaut syndrome and in 20 healthy children. High levels of a precipitating antibody to a saline extract of brain tissue were detected in all patients; leucocyte migration inhibition test with the same antigen was found to be positive in most of them. The role of th...

PURPOSE Hypsarrhythmia, the pathognomonic EEG pattern of West syndrome, is typically characterized by a high amplitude, arrhythmic, and asynchronous pattern. While this severely aberrant pattern would suggest severe abnormalities in connectivity, coherence has not yet been systematically assessed in hypsarrhythmia. METHODS We evaluated the EEGs of 28 infants, 12 with infantile spasms with hyp...

PURPOSE To determine if there are differences in the timing of diagnosis and response to treatment between infants with infantile spasms (IS) and Trisomy 21 (T21) and those with idiopathic IS. METHOD This was a retrospective study evaluating the time from onset of IS to diagnosis, treatment of IS, time from treatment to resolution of IS, and development of epilepsy in children with T21 and IS...