In vitro multiple shoots, root, callus and cell suspension cultures of Withania somnifera exhibited the potentiality to produce pharmacologically active withanolides. Multiple shoots cultures exhibited an increase in withanolide A accumulation compared to shoots of the mother plant. In vitro generated root cultures as well as callus and suspension cultures also produced withanolides albeit at l...

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1. The Indian Herbal Pharmacoepia. Regional Research Laboratory and Indian Drug Manufacturers Association. Mumbai: IDMA; 2002. p. 467. 2. Archana R, Namasivayam A. Antistressor effect of Withania somnifera. J Ethnopharmacol 1999;64:91-3. 3. Jha NK, Jha AK. Bacopa monnieri: Brahmi. Phytopharm 2005;11:3-14. 4. Gupta AP, Mathur S. High performance thin layer chromatography method for determination...

background urinary tract infections (uti) caused by resistant bacteria are becoming more prevalent. the spread of extended-spectrum beta-lactamase (esbl)-producing bacteria worldwide has become a serious public health issue among healthcare centers and in the community. drugs and many secondary metabolites from medicinal plants have proved to be economical and effective against many pathogens. ...

Phytochemical and Pharmacological Profile of Withania somnifera Dunal: A ReviewQamar Uddin, L. Samiulla, V. K. Singh, S. Jamil

results the results showed that the isolated e. coli strains were sensitive to these antibiotics: erythromycin (52.94%), tetracycline (76.47%), ceftazidime (41.17%), cefixime (35.29%), penicillin (76.47%), ampicillin (58.82%) and nalidixic acid (41.17%). examination of the herbal extracts showed that the highest maximum inhibitory concentration (mic) against drug resistant e. coli was 200 ppm. ...

Phytochemical and Pharmacological Profile of Withania somnifera Dunal: A ReviewQamar Uddin, L. Samiulla, V. K. Singh, S. Jamil

Administration of an extract from the powdered root of the plant Withania somnifera was found to stimulate immunological activity in Babl/c mice. Treatment with five doses of Withania root extract (20 mg/dose/animal; i.p.) was found to enhance the total WBC count (17125 cells/mm(3)) on 10th day. Bone marrow cellularity (27x10(6) cells/femur) as well as alpha-esterase positive cell number (1800/...

conclusions this study confirmed the antimicrobial potential of investigated plants and their usefulness in treatment of resistant isolates of k. pneumoniae. results the isolates of k. pneumoniae were resistance to four of the agents including ceftazidime (60% of isolates) cefixime (60% of isolates), erythromycin (66.6% of isolates). the highest mic values of extract were found to be 250 ppm ag...