In the present study, we assessed the incidence of adverse events and influenza-like symptoms in a working population in Switzerland that was vaccinated against influenza. A total of 12,582 individuals of working age (<65 years old) were offered a free influenza vaccine of their choice (injectable or intranasal vaccine) in October and November 2000. Of these individuals, 1600 were vaccinated ag...

We present a model of efficient regulation along the lines of Demsetz (1967). In this model, setting up and running regulatory institutions takes a fixed cost, and therefore jurisdictions with larger populations affected by a given regulation are more likely to have them. Consistent with the model, we find that higher population U.S. states have more pages of legislation and adopt particular la...

Compelling behavioral evidence suggests that humans can make optimal decisions despite the uncertainty inherent in perceptual or motor tasks. A key question in neuroscience is how populations of spiking neurons can implement such probabilistic computations. In this article, we develop a comprehensive framework for optimal, spike-based sensory integration and working memory in a dynamic environm...

Various visual cues provide information about depth and shape in a scene. When several of these cues are simultaneously available in a single location in the scene, the visual system attempts to combine them. In this paper, we discuss three key issues relevant to the experimental analysis of depth cue combination in human vision: cue promotion, dynamic weighting of cues, and robustness of cue c...

This paper aims at explaining how intermediaries influence collaborative innovation projects, suggesting a conceptual-theoretical framework about intermediaries’ roles and practices. The qualitative research was developed through the case study of the Orange Service Call and Reward project performed by the National Endowment for Science, Technology and the Arts (NESTA) for Orange Labs, the R&D ...