UNLABELLED Introduction. Silver dressings are widely used in the treatment of chronic wounds to reduce bacterial bioburden. However, little is known about the mechanism of silver ions on the healing process. In this study, a mouse model of wound healing was used to examine the effect of silver dressings in normal and diabetic wounds. METHODS Two 5-mm full-thickness wounds were created on t...

Background: The process of wound healing involves integrated events including inflammation, granulation tissue formation, matrix deposition and remodeling. Growth factors play a key role in the process. Among them transforming growth factor-ß1 (TGF-ß1) is known to accelerate tissue repair by promoting the synthesis and deposition of extracellular matrix proteins. However, persistence or overact...

Many patients present with wounds which are bleeding or prone to bleeding, and so cannot be treated with a noninteractive dressing. These wounds include: 8 Partialand full-thickness wounds 8 Arterial and venous ulcers 8 Diabetic foot ulcers 8 Pressure ulcers 8 Fungating lesions 8 Post-surgical wounds 8 Toe nail avulsions 8 Donor sites 8 Traumatic wounds 8 Wounds post debridement (sharp, surgica...

background and purpose: vitamin c is administered orally or intravenously for the treatment of burn wounds. however, effects of the topical application of vitamin c remain unclear. this study aimed to evaluate the effects of topical vitamin c solution on the necrotic tissue volume of second-degree burn wounds. methods: this clinical trial was conducted on 30 patients with second-degree burns ad...

background: this study was designed to investigate the efficacy of pentoxifylline (ptx) in the treatment of irradiated wounds. materials and methods: ten female pigs of the large white strain were used in these investigations. six skin fields, 4 * 4 cm and separated from each other by 4 cm, were marked out on each flank and those on left flank were irradiated with 18gy single dose of 250 kv x-r...

results: patients in the case and control groups were similar in age and admission vital signs. during the second operation, the bleeding volumes measured in the case and control groups were 66 ± 27.01 ml and 152 ± 85.4 ml, respectively. there was some pad-induced damage after the removal of the pad in the control group. patients and methods: twenty male patients with grade iv or v liver injuri...

background there is significant prevalence of physical injuries sustained by civilian recruits at military training garrisons. civilian recruits sustain these injuries mostly during the intensive and rigorous military combat-training period. objectives we sought to determine the prevalence and causes of oral and maxillofacial injuries as the first step in reducing and preventing them in civilia...

Wounds are of great concern in animals as they affect animal productivity and their treatment represents an economic burden to the owners particularly in developing countries. The present study investigated the beneficial role of a mixture of cod liver oil and honey in treatment of old wounds in equines. In which, 3 horses and 7 donkeys were admitted to the Veterinary Teaching Hospital at Assiu...

OBJECTIVE To evaluate the effects of low-level laser therapy (LLLT) on acute, full-thickness wound healing in dogs. STUDY DESIGN Randomized block (dog); historical control. ANIMALS Adult male Beagles (n = 10). METHODS Two 2 × 2 cm(2) wounds were surgically created bilaterally on the trunk of each dog. Each side was randomized to receive LLLT (laser, LAS) or standard-of-care management (co...