BACKGROUND Facial wrinkles are an undesirable feature caused by extrinsic photodamage and intrinsic aging process. Many cosmetic products and esthetic procedures strive to ameliorate the appearance of wrinkles. Currently the effects of those products and procedures on wrinkles are mainly evaluated by clinical grading, subjective self-assessment questionnaires, and optical profilometry of replic...

We compared age-related changes in wrinkles in eight areas of facial skin (forehead, glabella, upper eyelid, corner of the eye, lower eyelid, nasolabial groove, cheek, and corner of the mouth) and sagging in the subzygomatic area of Caucasian females and of Japanese females. The subjects studied included 85 healthy Caucasian females (ages 20-69 years) living in Cincinnati in the U.S. and 70 Jap...

Background. Uncontrolled melanogenesis and wrinkle formation are an indication of photoaging. Our previous studies demonstrated that (Z)-5-(2,4-dihydroxybenzylidene)thiazolidine-2,4-dione (MHY498) inhibited tyrosinase activity and melanogenesis in vitro. Objective. To examine in vivo effects of MHY498 as an antiaging compound on UVB-induced melanogenesis and wrinkle formation, we topically appl...

Surface wrinkling instability is typically caused by compressive stresses in layered systems. In a bilayer system with a stiff surface layer on a drastically more compliant substrate, spontaneous wrinkle patterns emerge as a result of the wrinkling instability. The wrinkle patterns can be controlled to form ordered surface structures, offering an unconventional method for microfabrication. [ 1–...

A thin elastic sheet lying on a soft substrate develops wrinkled patterns when subject to an external forcing or as a result of geometric incompatibility. Thin sheet elasticity and substrate response equip such wrinkles with a global preferred wrinkle spacing length and with resistance to wrinkle curvature. These features are responsible for the liquid crystalline smectic-like behaviour of such...

We investigated the surface reformation of poly(dimethylsiloxane) (PDMS) elastomers by means of ion beam bombardment for fabricating wrinkle structures. Oxidation on the PDMS surface formed a silica-like outer layer that interacted with the inner PDMS layer, leading to the formation of wrinkle structures that minimized the combined bending energy of the outer layer and stretching energy of the ...

[1] Recent Mars Orbiter Laser Altimeter (MOLA) data have provided a new picture of the Martian northern lowland basin topography and surface roughness. In order to assess detailed topographic structure important in understanding the formation and evolution of the northern lowlands, we have removed regional slopes from the topography to produce a series of maps highlighting the local topographic...

[1] A global assessment of impact craters on Venus 30 km in diameter shows that 146 craters are completely or partially superposed on the regional plains that dominate the surface and typically are deformed by wrinkle ridges. In this study, we found that 10 of these craters are deformed by wrinkle ridges (pre-WR), 93 craters are superposed on wrinkle ridges (post-WR), and 43 craters were found ...

Categorization of facial wrinkles is used in dermatology studies to determine the efficacy of a certain treatment over a certain period of time. These studies, however, are limited by the fact that when dermatologists assign these categorizations, it is done so through qualitative, in-vivo observation. The objective of this study was to train a computer to categorize nasolabial wrinkles into on...

Submitted for the MAR10 Meeting of The American Physical Society Draping Films: A Wrinkle to Fold Transition DOUGLAS HOLMES, Princeton University, ALFRED J. CROSBY, Universtity of Massachusetts Amherst — This work focuses on the wrinkle-to-fold transition in glassy and elastomeric thin films. In biological systems, the process of folding is critical to morphogenesis, defining such features as t...