The aim of this study was to determine if reliable patient-specific wall shear stress (WSS) can be computed when diameter-based scaling laws are used to impose the boundary conditions for computational fluid dynamics. This study focused on mildly diseased human coronary bifurcations since they are predilection sites for atherosclerosis. Eight patients scheduled for percutaneous coronary interve...

Although wall shear stress (WSS) has long been considered a critical indicator of intracranial aneurysm rupture, there is still no definite conclusion as to whether a high or a low WSS results in aneurysm rupture. The reason may be that the effect of WSS direction has not been fully considered. The objectives of this study are to investigate the magnitude of WSS (|WSS|) and its divergence on th...

BACKGROUND Wall shear stress (WSS) is a stimulus for vessel wall remodeling. Differences in ascending aorta (AAo) hemodynamics have been reported between bicuspid aortic valve (BAV) and tricuspid aortic valve patients with aortic dilatation, but the confounding impact of aortic valve stenosis (AS) is unknown. METHODS AND RESULTS Five hundred seventy-one subjects underwent 4-dimensional flow m...

INTRODUCTION Wall shear stress (WSS) plays a key role in the onset and progression of atherosclerosis in human coronary arteries. Especially sites with low and oscillating WSS near bifurcations have a higher propensity to develop atherosclerosis. WSS computations in coronary bifurcations can be performed in angiography-based 3D reconstructions. It is essential to evaluate how reconstruction err...

Service Based Systems, composed of Web Services (WSs), offer promising solutions to software development problems for companies. Like other software artefacts, WSs evolve due to the changed user requirements and execution contexts, which may introduce poor solutions—Antipatterns—may cause (1) degradation of design and quality of service (QoS) and (2) difficult maintenance and evolution. Thus, t...

INTRODUCTION Wall shear stress (WSS) may play a vital role in the pathogenesis and pathophysiology of aneurysms. Meng et al. showed that elevated peak longitudinal WSS may initiate aneurysm formation [1], whereas Boussel et al. demonstrated that low peak longitudinal WSS may contribute to aneurysm growth [2]. While measurements of WSS have been investigated within the aneurysmal bodies, the dow...

This study looks at blood flow in four different human right coronary arteries (RCAs), which have been reconstructed from bi-plane angiograms. A generalized power-law model of blood viscosity is used to study the blood flow at a particular point in the cardiac cycle. Large differences are found in the wall shear stress magnitude (WSS) distributions in the four arteries, leading to the conclusio...

From: WSS TC Chairs To: Karl Best, OASIS Dear Karl, Per the OASIS process document [1], we Kelvin Lawrence and Chris Kaler, co-Chairs of the WSS TC [2], have prepared the following document to accompany the submission from the WSS TC to OASIS of the Web Services Security specification and related documents for final approval as an OASIS standard. The TC voted to re-approve the documents [3], [4...

BACKGROUND AND PURPOSE Wall shear stress (WSS) is one of the main pathogenic factors in the development of saccular cerebral aneurysms. The magnitude and distribution of the WSS in and around human middle cerebral artery (MCA) aneurysms were analyzed using the method of computed fluid dynamics (CFD). METHODS Twenty mathematical models of MCA vessels with aneurysms were created by 3-dimensiona...

Objective The objective was to study the performance of an in-house developed wall shear stress (WSS) algorithm using PC-MRI in intracranial aneurysms. Materials & Methods First, the algorithm was applied to a high resolution in vitro PC-MRI measurement under steady and pulsatile fl ow conditions. A CFD simulation was performed with similar infl ow boundary conditions. Second, WSS was estimated...