Objective(s):To determine the molecular and cellular mechanisms of spinal cord regeneration in zebrafish. Materials and Methods: Medical databases of PubMed and Scopus were searched with following key words: Zebrafish; spinal cord injuries; regeneration; recovery of function. The map of mechanisms was performed using Xmind software. Results: Wnt/ß-catenin signaling, L1.1, L1.2, Major vault prot...

Carbendazim, a common pesticide, has shown signs of causing cancer, infertility and toxicity to organisms. Due its intense use, this fungicide become persistent compound in the environment, raising importance better understanding behaviour, metabolic pathways effects on Zebrafish is considered an excellent animal model, being able rapidly absorb compounds water, mimicking what occurs aquatic en...

Zebrafish are teleosts (bony fish) that share with mammals a common ancestor belonging to the phylum Osteichthyes, from which their endoskeletal systems have been inherited. Indeed, and numerous genetically conserved features in terms of skeletal elements, ossification mechanisms, bone matrix components common. Yet differences related morphology function need be considered when investigating ze...

ABSTRACT In vertebrate photoreceptors, opsins are highly concentrated in a morphologically distinct ciliary compartment known as the outer segment (OS). Opsin is synthesized cell body and transported to OS at remarkable rate of 100 1000 molecules per second. transport defects contribute photoreceptor loss blindness human ciliopathies. Previous studies revealed that rhodopsin C-terminal tail, 44...

background: ferroportin (fpn), a regulator of iron homeostasis is a conserved membrane protein that exports iron across the enterocytes, macrophages and hepatocytes into the blood circulation. fpn has also critical influence on survival of microorganisms whose growth is dependent upon iron, thus preparation of fpn is needed to study the role of iron in immunity and pathogenesis of micoorganisms...

The herbicides used in agriculture threaten aquatic ecosystems and biodiversity on a global scale. There are several reports on the residues of currently used herbicides in the tissues of aquatic organisms. This study aimed to determine the effect of concentration on the accumulation of Butachlor in liver tissue in zebrafish fish exposed to sub-lethal concentrations of the toxin. In this study,...