Zipper fractal interpolation function (ZFIF) is a generalization of through an
 improved version iterated system by using binary parameter called signature. The signature
 allows the horizontal scalings to be negative. ZFIFs have complex geometric structure, and they can
 non-differentiable on dense subset an interval I. In this paper, we construct k-times continuously
 diff...

Membrane fusion plays a central role in biological processes such as neurotransmission and exocytosis. An important class of proteins that induce membrane fusion are called SNARE (soluble N-ethyl malemeide sensitive factor attachment protein receptors) proteins. To induce membrane fusion, two SNARE proteins embedded in opposing membranes form a four-helix coiled-coil motif together with a third...

The leucine zipper is the dimerization domain of the B-ZIP (basic-region leucine zipper) class of eukaryotic transcription factors (Vinson et al., 1989). The name arose because leucines occur every seven amino acids in this dimerization domain.These leucines are critical for the dimerization and DNA binding of B-ZIP proteins. The leucine zipper is a left-handed parallel dimeric coiled-coil, a s...

Zipper logic is a graph rewrite system, consisting in only local rewrites on a class of zipper graphs. Connections with the chemlambda artificial chemistry and with knot diagrammatics based computation are explored in the article.

The question of whether a protein whose natural sequence is inverted adopts a stable fold is still under debate. We have determined the 2. 1-A crystal structure of the retro-GCN4 leucine zipper. In contrast to the two-stranded helical coiled-coil GCN4 leucine zipper, the retro-leucine zipper formed a very stable, parallel four-helix bundle, which now lends itself to further structural and funct...

The determination of structural and nonstructural damage under earthquake excitations is usually considered as a key factor in performance-based seismic design (PBSD) methods is In this regard, various damage indices have been developed in recent years to quantitatively estimate structural damage. The aim of this study is to develop a simple method to evaluate performance levels of zipper-brace...

TFE3 is a DNA-binding protein that activates transcription through the muE3 site of the immunoglobulin heavy-chain enhancer. Its amino acid sequence reveals two putative protein dimerization motifs: a helix-loop-helix (HLH) and an adjacent leucine zipper. We show here that both of these motifs are necessary for TFE3 to homodimerize and to bind DNA in vitro. Using a dominant negative TFE3 mutant...

Introduction: Clinical reasoning is a vital aspect of physiciancompetence. It has been the subject of academic research fordecades, and various models of clinical reasoning have beenproposed. The aim of the present study was to develop a theoreticalmodel of clinical reasoning.Methods: To conduct our study, we applied the process of theorysynthesis in accordan...

Background: We have done a prospective, controlled, randomized study to investigate the role of the “zipper”, a new device for skin closure. We have also analysed morbility and advantages with the use of the “zipper” compared with sutures. Methods: 610 consecutive patients underwent surgery for abdominal thoracic endocrinologic and post traumatic pathologies. In 203 cases we used the zipper a n...

In many distributed applications, pairs of queries and values are evaluated by participating nodes. This includes keyword search for documents, selection queries on tuples, and publish-subscribe. These applications require that all values accepted by the query be evaluated. To carry out this evaluation we will present the peer-to-peer based Bit Zipper Rendezvous which partitions query-value pai...