The inactivation of the Zn+2 metallo enzyme acylamino acid amido hydrolase from Aspergillus oryzae by ethylendiamine-tetraacetate (EDTA) and nitrilotriacetate (NTA) and the effects of Phe and His on this process were studied. Reactivation of the enzyme by Zn+2or Co+2-NTA buffer revealed a dissociation constant for the Zn+2-enzyme of 10~10 M and for the Co+2-enzyme of 10-7-5 m. The kinetic prope...

Objectives: To clarify the role of trace elements in the etiology and the pathogenesis of the osteogenic sarcoma (osteosarcoma), a non-destructive neutron activation analysis with high resolution spectrometry of long-lived radionuclides was performed. Methods: The silver (Ag), cobalt (Co), chromium (Cr), iron (Fe), mercury (Hg), rubidium (Rb), antimony (Sb), selenium (Se), and zinc (Zn) mass fr...

concentrations of major nutritional and trace elements (ca, p, mg, na, k, fe, zn, cu, mn, se,co, cr, ni, sr, ba) and toxic heavy metals (cd, pb) were analyzed in the meat of limousin, red angus andsalers bulls. elements were determined using inductively coupled plasma emission atomic spectrometry. theconducted research showed that the meat of compared breeds differed in the concentrations of cu...

The photoreceptor cGMP phosphodiesterase (PDE6) plays a key role in vertebrate vision, but its enzymatic mechanism and the roles of metal ion co-factors have yet to be determined. We have determined the amount of endogenous Zn in rod PDE6 and established a requirement for tightly bound Zn in catalysis. Purified PDE6 contained 3–4-g atoms of zinc/mole, consistent with an initial content of two t...

Materials and Methods: The silver (Ag), cobalt (Co), chromium (Cr), iron (Fe), mercury (Hg), rubidium (Rb), antimony (Sb), selenium (Se), and zinc (Zn) content and Co/Ag, Cr/Ag, Fe/Ag, Hg/Ag, Sb/Ag, Se/Ag, Co/Rb, Cr/Rb, Fe/Rb, Hg/Rb, Sb/ Rb, Se/Rb, Co/Zn, Cr/Zn, Fe/Zn, Hg/Zn, Sb/Zn, and Se/Zn ratios were estimated in normal bone samples from 27 patients with intact bone (12 females and 15 males...

Heavy metal contamination around the National Iranian Lead and Zinc Company (NILZ) in Zanjan province was evaluated in this paper. Collected data were used to appraise the degree of soil contamination and also the source of pollution in the study area based on geoaccumulation index (Igeo), and enrichment factor (EF). The levels of Fe, Zn, Cd and Pb in the samples exceed those reported in litera...

background: cadmium (cd) is a heavy metal that has widespread use. it enters the food chain in different ways, including soil and water. cadmium can cause dysfunction of different body organs. zinc (zn) and magnesium (mg) supplementation can have protective effects against cadmium toxicity due to their antagonistic and antioxidants properties. this study examines the influence of supplemental z...

phthalocyanine complexes of cu, co, ni, fe, zn, pd, pt and ru have been synthesized from reaction between phthalonitrile and proper metal salts upon exposure to microwave irradiation under solvent-free conditions and considerably reduced reaction times.