Patients who recover from leishmaniasis usually show development of strong immunity and induction of interferon-γ (IFN-γ) and delayed type hypersensitivity. In a randomized trial, we analyzed the IFN-γ response by using a Quantiferon-Leishmania assay against three Leishmania peptide antigens and compared it with results of the leishmanin skin test (LST) in persons residing in areas in Iran to w...

introduction cutaneous leishmaniasis (cl) is one of the most important zoonotic diseases in iran. according to the reports of the center for disease management and control, among the 20,000 cases infected with various types of leishmaniasis annually, 80% are zoonotic cutaneous leishmaniasis (zcl). this descriptive and retrospective study was performed to determine the most recent status of zcl ...

background: leishmaniasis is a zoonotic disease caused by species of protozoa of the genus leishmania . in recent years, incidence of cutaneous leishmaniasis has increasing trend in golestan province, north of iran. the aim of the present study was to identify the frequency of cutaneous leishmaniasis using pcr-rflp in patients referred to kalaleh health center, during 2013-14. methods: this des...

Background and aims: Cutaneous leishmaniasis is a major health issue in many parts of Iran.Diagnosis of cutaneous leishmaniasis in a non-endemic area is not as simple as that in endemic foci.The management and treatment of this disease are global dilemmas. The purpose of this study was toidentify Leishmania species isolated from human cutaneous leishmaniasis lesions in patient...

Background & Aims: Despite improvements in public health in Iran, cutaneous leishmaniasis has become a growing health issue. About 90% of cutaneous leishmaniasis cases occur in 8 countries including Iran. Kala-azar or visceral leishmaniasis, as an important parasitic disease, is endemic in some areas of Iran. Mapping the distribution of parasitic diseases and determining their relations to geog...

Leishmaniasis has long been known as a significant public health challenge in many parts of Iran. Phlebotomus papatasi and P. sergenti are the vectors of Zoonotic Cutaneous Leishmaniasis and Anthroponotic Cutaneous Leishmaniasis respectively, and 5 species of sand flies including P. kandelakii, P. neglectus, P. perfiliewi, P. keshishiani and P. alexandri are considered as probable vectors of Zo...

BACKGROUND Leishmaniasis is a zoonotic disease caused by species of protozoa of the genus Leishmania. In recent years, incidence of cutaneous leishmaniasis has increasing trend in Golestan Province, North of Iran. The aim of the present study was to identify the frequency of cutaneous leishmaniasis using PCR-RFLP in patients referred to Kalaleh Health Center, during 2013-14. METHODS This desc...

Following an epidemiological survey of zoonotic cutaneous leishmaniasis (ZCL) in several villages of Badrood, a rural district north of the city of Natanz, central Iran, Phlebotomus (Phlebotomus) papatasi Scopoli were found to be naturally infected with Leishmania (Leishmania) major zymodeme MON-26. Sand flies were collected and dissected biweekly from rodent burrows from May to October 2001. L...

in 5 villages in isfahan area, with a population of 1368, rodents were successfully controlled using poisened bait with zinc phospheid, with 300 meters of houses and built up area. in another 5 villages with a population of 1471, rodent burrows were dusted with ddt within the same distance, without any effect on sandflies. a third group of 5 villages was kept as control. the incidence of cutane...