Calculations are presented for the glycine–(H2O)3 cluster anion, with glycine in canonical or zwitterionic form. The zwitterionic anions are predicted to be considerably lower in energy than the canonical anions, and the latter forms are found to be prone to isomerization to the zwitterionic anions. Therefore, we predict that the zwitterionic anions would be observed predominantly in the gas ph...

Antimicrobial coating is of great important in leather finishing. Herein, we report a newly synthesized polyurethane with zwitterionic sulfobetaine side groups and evaluate their performance in the antifouling leather coatings. The microstructure of the synthesized zwitterionic polyurethane (iNPU) films has been examined by Fourier transform infrared (FTIR), X-ray diffraction (XRD) and atomic f...

Previously we have shown that palladium catalysts effect the decarboxylation of vinyl oxazinones to form zwitterionic π-allyl palladium intermediates (A, Scheme 1).1 Thus, vinyl oxazinones can be equated with zwitterionic synthons (B). In the absence of other electrophiles, the zwitterionic intermediate cyclizes to form vinyl azetidines with high diastereoselectivity. Moreover, in the presence ...

Meta-aminobenzoic acid, an important model system in the study of polymorphism and crystallization of active pharmaceutical ingredients, exist in water in both the nonionic (mABA) and zwitterionic (mABA±) forms. However, the constituent molecules of the polymorph that crystallizes from aqueous solutions are zwitterionic. This study reports atomistic simulations of the events surrounding the ear...

Mesoporous hybrid silica bearing zwitterionic species were synthesized via template-directed hydrolysis-polycondensation reactions from zwitterionic ammonium sulfonate precursors. The formation of the nanostructured phases involves specific precursor-template interactions. The obtained materials are efficient heterogeneous catalysts in Biginelli reactions.

Gold nanoparticles (AuNPs) were assembled with high density onto multi-walled carbon nanotubes, which were functionalized with zwitterionic poly(imidazoliumsulfonate). The AuNP/zwitterionic CNT hybrids exhibited decent electrocatalytic activity in oxygen reduction reaction as the AuNP-based catalysts.

Structural characterization of proteins in the gas phase is becoming increasingly popular, highlighting the need for a greater understanding of how proteins behave in the absence of solvent. It is clear that charged residues exert significant influence over structures in the gas phase due to strong Coulombic and hydrogen-bonding interactions. The net charge for a gaseous ion is easily identifie...

Cationic and anionic residues of the extracellular matrices (ECM) of bone play synergistic roles in recruiting precursor ions and templating the nucleation, growth and crystalline transformations of calcium apatite in natural biomineralization. We previously reported that zwitterionic sulfobetaine ligands can template extensive 3-dimensional (3-D) hydroxyapaptite (HA)-mineralization of photo-cr...

Long-circulating drug carriers are highly desirable in drug delivery system. However, nonspecific protein adsorption leaves a great challenge in drug delivery of intravenous administration and significantly affects both the pharmacokinetic profiles of the carrier and drugs, resulting in negatively affect of therapeutic efficiency. Therefore, it is important to make surface modification of drug ...