The dichloromethane and ethyl acetate extracts from the bark of Garcinia hombroniana yielded lupeol (1), lupeol acetate (2), 3β-acetoxylup-12,20(29)-diene (3), β-sitosterol (4), 22-dehydroclerosterol (5), mangiferolic acid (6), ursolic acid (7), betulin (8), betulinic acid (9), 1,3,6-trihydroxy-7-methoxy-2,8-(3-methyl2-butenyl)xanthone (10), leucodin (11), p-hydroxycinnamate (12), p-hydroxybenz...

IN THE TITLE COMPOUND [SYSTEMATIC NAME: 5-(5,7-dihydr-oxy-4-oxo-4H-chromen-yl)-2-hydroxy-benzene-sulfonic acid dihydrate], C(15)H(10)O(8)S·2H(2)O, the benzopyran-one ring is not coplanar with the phenyl ring, the dihedral angle between them being 41.35 (3)°. No H atom was placed on the sulphonic acid group because it was not possible to distinguish between the two S=O bonds and the S-O bond. In...

Heparin-based anticoagulants are drugs of choice in the therapy and prophylaxis of thromboembolic diseases. Idraparinux is a synthetic anticoagulant pentasaccharide based on the heparin antithrombin-binding domain. In the frame of our ongoing research aimed at the synthesis of sulfonic acid-containing heparinoid anticoagulants, we elaborated a modular pathway to obtain a series of idraparinux-a...

Catalytic activities of eight sulfonic acid group functionalized ionic liquids in water were compared for the hydrolysis of Sigmacell cellulose (DP ~ 450) in the 150-180°C temperature range by measuring total reducing sugar (TRS) and glucose produced. The catalytic activity of acidic ionic liquids with different cation types decreases in the order imidazolium > pyridinium > triethanol ammonium ...

The preparation of 5-bromo-2-naphthol (4) in three steps from 5-amino-2-naphthol (1) is described. A sulfonic acid group is introduced at the 1-position as an activating and protecting group for the Sandmeyer reaction. The sulfonate group allows for the use of only water and sulfuric acid as solvents. The sulfonic acid is introduced with three equivalents of sulfuric acid, and it is removed in ...

BACKGROUND Exposure to perfluorooctane sulfonic acid (PFOS) or to perfluorooctanoic acid (PFOA) increases mouse and human peroxisome proliferator-activated receptor alpha (PPARα) subtype activity, which influences lipid metabolism. Because cholesterol is the substrate from which testosterone is synthesized, exposure to these substances has the potential to alter testosterone concentrations. O...