Millions of years of evolution have resulted in an immense number of different proteins, which participate in virtually every process within cells and thus are of utmost importance for all known forms of life. In addition, there are several examples of natural proteins which have found use in applications outside their natural environment, such as the use of enzymes in food industry and washing...

Introduction: Multi-drug resistant Gram negative bacilli are increasingly being isolated from hospitals throughout the world. The aim of this study was to determine the antimicrobial susceptibility profile of Gram negative bacterial isolates obtained from various clinical samples of patients admitted in different ICUs and wards of a super-specialty hospital during 2014. Materials and Methods: A...

Introduction: Skin and soft tissue infections (SSTI’s) are commonly caused by both gram positive and gram negative bacteria. The aim of the study was to investigate the presence of methicillin resistant Staphylococcus aureus (MRSA), Extended Spectrum Beta Lactamase (ESBL), Amp C and Metallo β-lactamase producing gram negative bacilli from clinical isolates obtained from patients attending G.S M...

In recent years, infections caused by multi-drug resistant (MDR) pathogens have become a serious problem, especially in the nosocomial setting. Th e World Health Organization (WHO) has identifi ed antimicrobial resistance as one of the three most important problems for human health. Some authors have summarized this pheno menon with the word ‘ESKAPE’, to include the most frequent MDR microorgan...

Environmental microorganisms represent the most relevant reservoir of resistance to antibiotics in the community, and this is due in part to the undue exposure of these organisms to antimicrobial agents. AmpC β-lactamases are clinically important cephalosporinases encoded on the chromosomes of bacteria in the Enterobacteriaceae family and some non-enteric bacteria including Pseudomonas aerugino...

Dairy farming in Uganda provides a source of food, employment and income. Previous studies have revealed high frequencies of bovine mastitis, a costly disease for the dairy farmer. The aims of this study were to investigate the bacteriological panorama in milk from udder quarters with clinical (CM) and subclinical mastitis (SCM) and to determine the antimicrobial susceptibility in staphylococca...

Klebsiella pneumoniae and Escherichia coli are pathogens belonging to the Enterobacteriaceae family. They can cause infections ranging from uncomplicated urinary tract infection to severe bloodstream infection (BSI). The prevalence of extended spectrum βlactamase-producing Enterobacteriaceae (EPE) is increasing worldwide and carbapenemases (CPE), a subgroup of EPE where antibiotic treatment is ...