II. Glutathione homeostasis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336 A. Synthesis and degradation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 336 B. Biological functions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....

Calibration is a concept that tries to formalize a notion of quality for forecasters. For example, suppose a weatherman predicts each day whether the it will rain, or be sunny. Typically forecasters will predict such events in terms of probabilities, i.e., “There is a 30% chance of rain.” Given only the outcome that day, it is impossible to judge the quality of such a forecast. However, if we c...

• For each player i, a partition Ii of {h ∈ H : P (h) = i} (i.e., each history occurs in exactly one of the sets in Ii), such that if h, h ∈ Ii, then A(h) = A(h). The collection Ii is the information partition of player i, and a member Ii ∈ Ii is an information set of player i. For any information set I , let P (I) and A(I) denote the player and action set corresponding to the information set. ...

The general transcription factor IIH is recruited to the transcription preinitiation complex through an interaction between its p62/Tfb1 subunit and the -subunit of the general transcription factor IIE (TFIIE ). We have determined that the acidic carboxyl terminus of TFIIE (TFIIE 336–439) directly binds the amino-terminal PH domain of p62/Tfb1 with nanomolar affinity. NMR mapping and mutagenesi...

Aggregatibacter actinomycetemcomitans produces a repeats-in-toxin (RTX) leukotoxin (LtxA) that selectively kills human immune cells. Binding of LtxA to its β2 integrin receptor (lymphocyte function-associated antigen-1 (LFA-1)) results in the clustering of the toxin·receptor complex in lipid rafts. Clustering occurs only in the presence of LFA-1 and cholesterol, and LtxA is unable to kill cells...

In this paper, following corrections should be made: (page 336, Fig. 4) Replace the figure as follows: (page 336, legend of Fig. 4, line 2) For " S-125 " Read " S-128 " (continues to the next page)

INTRODUCTION ................................................................................. 325 CELL STRUCTURE............................................................................... 325 BIOLOGICAL ACTIVITIES................................. 326 AGGLUTINOGEN................................................. 327 HEMAGGLUTININ ................................. 329 HEAT-LABILE TOXIN.........

The expression of the cannabinoid peripheral cannabinoid receptor (CB(2)) receptor on peripheral immune cells suggests that compounds specific for CB(2) might be effective anti-inflammatory agents. In this report, we present the initial biological profiling of a novel triaryl bis-sulfone, Sch.336 (N-[1(S)-[4-[[4-methoxy-2-[(4-methoxyphenyl)sulfonyl]phenyl]-sulfonyl]phenyl]ethyl]methanesulfonami...

To compare the performance of steer calves managed under different stocking rates (SR; 3.7, 6.2, 8.6, and 11.1 steers/ha for 140 d; chi(I1)) and N fertilization rates (112, 224, and 336 kg of N/ha; chi(I2)) in May 1996, 1997, and 1998, 72 steer calves (BW = 231 +/- 2.5 kg) were assigned randomly to one of 12 0.81-ha dallisgrass (51%)/common bermudagrass (32%) pastures. One-third of the fertiliz...