Corresponding author: Dae-Young Kim, M.D., Department of Anesthesiology and Pain Medicine, Ulsan University Hospital, Junhwa-dong, Dong-gu, Ulsan 682-714, Korea. Tel: 82-52-250-7248, Fax: 82-52-250-7249, E-mail: [email protected] This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/3.0/...

It is understood gait has the potential to be used as a window into neurodegenerative disorders, identify markers of subclinical pathology, inform diagnostic algorithms of disease progression and measure the efficacy of interventions. Dogs' gaits are frequently assessed in a veterinary setting to detect signs of lameness. Despite this, a reliable, affordable and objective method to assess lamen...

Bouncing oil droplets have been shown to follow de Broglie-Bohm like trajectories and at the same time they exhibit attractive and repulsive pseudo-gravitation. We propose a model aimed at rendering account of these phenomenological observations. It inspires, in a more speculative approach, a toy model for quantum gravity. In studies concerning quantum wave mechanics, de Broglie-Bohm (dB-B) tra...

E pidemiological studies have shown that about 43–86% of individuals with tuberous sclerosis complex have a pervasive developmental disorder similar to autism. Mutations in tuberous sclerosis genes TSC1 and TSC2 disrupt the phosphatidylinositol signalling pathway downstream of the insulin / insulin-like growth factor receptor in the control of cell growth. We investigated single nucleotide poly...

DNA-based nanostructures built from a long single-stranded DNA scaffold, known as DNA origamis, are at the basis of many applications. Despite their widespread development, many basic questions concerning the mechanisms of formation of DNA origamis have not yet been addressed. For instance, the robustness of different designs against factors such as the internal topology, or the influence of th...

The hydroxylase component (MMOH) of the multicomponent soluble methane monooxygenase (MMO) system catalyzes the oxidation of methane by dioxygen to form methanol and water at non-heme, dinuclear iron active sites. The catalytic cycle of MMOH is well established.1,2 Following reduction of the Fe(III)Fe(III) resting enzyme to the Fe(II)Fe(II) state, two spectroscopically observable intermediates,...