The beneficial actions of caloric restriction (CR) are partially mediated by metabolic remodeling of white adipose tissue (WAT). Recently, we showed that CR enhances de novo fatty acid (FA) biosynthesis and mitochondrial biogenesis, particularly in WAT. Here, to better understand the response of WAT to CR, we compare the effects of CR on three WAT depots in rats: retroperitoneal (rWAT), epididy...

The ability of a watershed model to mimic specified watershed processes is assessed through the calibration and validation process. The Soil and Water Assessment Tool (SWAT) watershed model was implemented in the Beaver Reservoir Watershed of Northwest Arkansas. The objectives were to: (1) provide detailed information on calibrating and applying a multisite and multivariable SWAT model; (2) con...

The objective of the research was to model water quality using the Soil and Water Assessment Tool (SWAT) interfaced with ArcView GIS. SWAT requires the integration of a range of GIS data layers; digital elevation model, soil types, land use, stream networks, water quality monitoring sites, point pollution sources and climatic observations. Prior to modeling water quality with SWAT, ArcView was ...

Macroscopic mechanical properties of human skin in vivo cannot be considered independent of adjacent subcutaneous white adipose tissue (sWAT). The layered system skin/sWAT appears as the hierarchical structural composite in which single layers behave as fiber-reinforced structures. Effective macroscopic mechanical properties of such composites are mainly determined either by the properties of t...

We will demonstrate the Secure Wireless Agent Testbed (SWAT), a unique facility developed at Drexel University to study integration, networking and information assurance for next-generation wireless mobile agent systems. SWAT is an implemented system that fully integrates: 1) mobile agents, 2) wireless ad hoc multi-hop networks, and 3) security. The demonstration will show the functionality of ...

Using the probably approximately correct (PAC) learning hypothesis, we have conducted experiments using clustered computers, high-performance workstations and ad-hoc grids of personal computers, to develop an analytical model for, and demonstrate asymptotic convergence of simple parallel search in the parameter space of complex environmental models such as the Soil and Water Assessment Tool (SW...

SWAT (Soil and Water Assessment Tool) is a comprehensive, semi-distributed river basin model that requires a large number of input parameters, which complicates model parameterization and calibration. Several calibration techniques have been developed for SWAT, including manual calibration procedures and automated procedures using the shuffled complex evolution method and other common methods. ...

The temptation to include model parameters and high resolution input data together with the availability of powerful optimization and uncertainty analysis algorithms has significantly enhanced the complexity of hydrologic and water quality modeling. However, the ability to take advantage of sophisticated models is hindered in those models that need a large number of input files, such as the Soi...

This paper proposes and evaluates a decentralized self-healing mechanism that detects and recovers from wormhole attacks in wireless multi-hop sensor networks. Upon detecting a wormhole attack, the proposed mechanism, called SWAT, identifies the locations of malicious nodes (or wormhole nodes), isolates them from the network and recovers the routing structure distorted by them. SWAT is the firs...

Calibration of large watershed models requires multi-gage calibration, however there are limited tools available for performing these calibrations of SWAT models. Non-Dominated Sorting Genetic Algorithm II (NSGA-II) has been shown to be an effective and efficient multi-objective calibration algorithm in various disciplines. Although NSGA-II has been used with SWAT before, there is no publically...