onion (allium cepa) bulb from liliaceae has antioxidant, spasmolytic and antihypertensive activities. the aim of present study was to investigate the antispasmodic effect of onion peel on rat ileum contractility. onion peel powder was extracted by maceration in 70% alcohol for 72 h. a terminal portion of ileum from male wistar rat was dissected and its contractions were recorded isotonically in...

The objective of the study was to evaluate the use of goat ileum preparation for the estimation of unknown concentration of acetylcholine by three point bioassay. The graded doses of acetylcholine have shown dose dependent increase in contraction of isolated goat ileum. The responses obtained by this tissue preparation were similar to those with guinea pig ileum preparation. The goat ileum can ...

background& objectives: zataria multiflora boiss is used in traditional medicine to treat gastrointestinal disorders and menorrhagia. the inhibitory effect of this herb on rat uterus contractions has also been reported. the aim of this study was to investigate the effect of zataria multiflora boiss hydroalcoholic leaf extract (zhle) on isolated rat ileum in presence of some known ileum stimulan...

Teucrium polium L. (Lamiaceae) is used in the traditional medicine of Iran for the treatment of disorders of the gastrointestinal tract. The essential oil from the aerial parts of T polium was assessed for antispasmodic activity and compared with the effect of atropine and dicyclomine. Acetylcholine and KC I were used for induction of contraction on rat isolated ileum. Teucrium polium essen...

Onion (Allium cepa) bulb from Liliaceae has antioxidant, spasmolytic and antihypertensive activities. The aim of present study was to investigate the antispasmodic effect of onion peel on rat ileum contractility. Onion peel powder was extracted by maceration in 70% alcohol for 72 h. A terminal portion of ileum from male Wistar rat was dissected and its contractions were recorded isotonically in...

To evaluate the effects of hyperglycemia and insulin treatment on proportion serotonin-immunoreactive (5-HT-IR) myenteric neurons, samples were taken from duodenum, ileum, colon diabetic, insulin-treated control rats 10 weeks after onset streptozotocin-induced hyperglycemia. Myenteric whole-mount preparations immunostained with anti-5-HT pan-neuronal anti-HuCD markers. In controls, 5-HT-IR neur...

Many studies dealing with trinitrobenzene sulfonic acid (TNBS) colitis in rats have been carried out referring only to the colon. In humans, ulcerative colitis (UC) can extend a variable distance into the terminal ileum in a phenomenon known as backwash ileitis (BWI). The aim of this study was therefore to examine the effect of TNBS-induced colitis on different aspects of the rat ileum and jeju...

background: sepsis related-multiple organ dysfunction is associated with ileum injury. we aimed to determine the causes of ileal injury in two models of microbial sepsis resulted from infection with aeromonas hydrophila or its endotoxin. we also evaluated the protective effect of phytic acid .   methods: thin sections of ileum from 60 swiss male mice in control, bacteria-infected or lipopolysac...

Rosa damascena flower is widely used for gastrointestinal (GI) disorders. However, its pharmacological action on isolated ileum has not been studied. In this research, the effect of extract of flower petals of R. damascena Mill. growing in Kashan, Iran, on ileum motility was investigated. Hydroalcoholic extract was prepared by percolation method. A section of rat ileum was suspended in an organ...