The 'mitotic spindle checkpoint' ensures that, before a cell exits from mitosis, all of its chromosomes are aligned on the spindle to form the metaphase plate. Mad2 is an essential component of this checkpoint system and it binds specifically to unattached kinetochores.

Abstract Examining women's magazines and lifestyle coaching, the article explores how positivity imperatives in contemporary culture call forth a happy, confident, hopeful, vibrant subject during COVID-19 pandemic. The analysis shows these acknowledge stress difficulty, at times highlight their gendered impacts, yet nevertheless systematically figure responses solutions individual, psychologica...