Anti-cytotoxic T lymphocyte antigen-4 (CTLA-4) treatment is effective for the treatment of primary tumors, but not sufficient for the treatment of metastatic tumors, likely owing to the effects of the tumor microenvironment. In this study, we aimed to determine the therapeutic effects of combined treatment with a matrix metalloproteinase (MMP) inhibitor (MMPI) and anti-CTLA-4 antibody in a brea...

Previous research has suggested that except for paranoid schizophrenics, similarity in diagnostic category has little effect on sociometric choice among patients. A sociometric study was conducted employing MMPI scales as well as diagnostic categories on 84 hospitalized psychiatric patients. When diagnostic labels from the patients' charts were used, results showed no relationship between socio...

Although PTSD-S was developed in 1987, it was evolved using the MMPI-2. The 53-item subset for the MMPI is presented in tabular form.

The MMPI-2 restructured clinical (RC) scales replace the traditional clinical scales in the MMPI-2 restructured form (MMPI-2-RF). Few studies to date have examined the MMPI-2 RC scales in traumatic brain injury (TBI) litigants. We compared MMPI-2 validity, clinical, and RC scales profiles of 83 mild, complicated mild, and moderate/severe TBI litigants who were tested for effort. Past research s...

Users of multi-scale tests like the MMPI-2 tend not to interpret scales one at a time in a way that would correspond to standard scale-level reliability information. Instead, clinicians integrate inferences from a multitude of scales simultaneously, producing a descriptive narrative that is thought to characterize the examinee. This study was an attempt to measure the reliability of such integr...

The current study examined the effectiveness of the MMPI-2 Restructured Form (MMPI-2-RF; Ben-Porath and Tellegen, 2008) over-reporting indicators in civil forensic settings. The MMPI-2-RF includes three revised MMPI-2 over-reporting validity scales and a new scale to detect over-reported somatic complaints. Participants dissimulated medical and neuropsychological complaints in two simulation sa...

The MMPI and MMPI-2 have been widely used in the assessment of persons with substance abuse problems. This highlight file notes some of the special contributions that were made showing that the MMPI scales are appropriate, reliable, and valid in predicting behavior pertinent to alcohol and drug abuse problems. The major research studies, both from historic and contemporary perspectives, are hig...

The MMPI-2 Restructured Form (MMPI-2-RF; Ben-Porath & Tellegen, 2008) is replacing the MMPI-2 as the most widely used personality test in neuropsychological assessment, but additional validation studies are needed. Our study examines MMPI-2-RF Validity scales and the newly created Somatic/Cognitive scales in a recently reported sample of 82 traumatic brain injury (TBI) litigants who either pass...

Despite their frequent conjoint clinical use, the incremental validity of Rorschach (Rorschach, 1921/1942) and MMPI (Hathaway & McKinley, 1943) data has not been adequately established, nor has any study to date explored the incremental validity of these tests for predicting Diagnostic and Statistical Manual of Mental Disorders (4th ed. [DSM-IV]; American Psychiatric Association, 1994) personal...

Introduction of a new version of a psychological test brings with it challenges that can be accentuated by the adversarial nature of the legal process. In the case of the Minnesota Multiphasic Personality Inventory-2 Restructured Form (MMPI-2-RF), these challenges can be addressed by becoming familiar with the rationale for and the methods used in revising the inventory, the information contain...