While the 26S proteasome is a key proteolytic complex, little is known about how proteasome levels are maintained in higher eukaryotic cells. Here we describe an RNA interference (RNAi) screen of Drosophila melanogaster that was used to identify transcription factors that may play a role in maintaining levels of the 26S proteasome. We used an RNAi library against 993 Drosophila transcription fa...

The most efficient way to parallelize computation is to build and evaluate the task graph constrained only by the data dependencies between the tasks. Both Intel’s C++ Concurrent Collections (CnC) and Threading Building Blocks (TBB) libraries allow such task-based parallel programming. CnC also adapts the macro data flow model by providing only single-assignment data objects in its global data ...

The four- and five-coordinate complexes [(CNC)NiX(2)] (X = Cl, Br, I), [(CNC)NiX]PF(6) (X = Cl, Br) and [(CNC)NiCl]Cl·H(2)O have been isolated, where CNC is the bis(N-butylbenzimidazolin-2-ylidene)-2,6-pyridine pincer ligand. A five-coordinate geometry is rare for this class of complex. Where amenable, the complexes have been structurally characterised by single crystal X-ray diffraction studie...

Sox9 has essential roles in endochondral bone formation during axial and appendicular skeletogenesis. Sox9 is also expressed in neural crest cells, but its function in neural crest remains largely unknown. Because many craniofacial skeletal elements are derived from cranial neural crest (CNC) cells, we asked whether deletion of Sox9 in CNC cells by using the Cre recombinase/loxP recombination s...

pH-sensitive poly(acrylic acid) (PAA) hydrogel reinforced with cellulose nanocrystals (CNC) was prepared. Acrylic acid (AA) was subjected to chemical cross-linking using the cross-linking agent MBA (N,N-methylenebisacrylamide) with CNC entrapped in the PAA matrix. The quantity of CNC was varied between 0, 5, 10, 15, 20, and 25 wt %. X-ray diffraction (XRD) data showed an increase in crystallini...

We discuss observations and seismic analyses for three multi-periodic δ Scuti stars in the Praesepe cluster: BU, BN and BV Cnc. For two stars (BU and BN Cnc) we re-analyse published photoelectric photometry and show that using statistical weights results in a dramatic reduction in the noise level. We detect seven frequencies in BU Cnc and eight in BN Cnc, with three of the latter being previous...

OBJECTIVE To compare clinical outcomes of elective central venous catheter (CVC) insertions performed by either a clinical nurse consultant (CNC) or anaesthetic medical staff (AMS). DESIGN, SETTING AND PARTICIPANTS Prospective audit of a convenience sample of consecutive CVC insertions between July 2005 and October 2007 at a metropolitan teaching hospital in Sydney, Australia. The sample incl...

The neural crest (NC) is a vertebrate-specific cell population that exhibits remarkable multipotency. Although derived from the neural plate border (NPB) ectoderm, cranial NC (CNC) cells contribute not only to the peripheral nervous system but also to the ectomesenchymal precursors of the head skeleton. To date, the developmental basis for such broad potential has remained elusive. Here, we sho...

This paper describes a model of knowledge-based system for integrating CAM and CNC operations. In detail, the main concern of integration is driven by proposed standardized check list as a part of product data which is useful for capturing and managing the knowledge based activities done by CAM operators and CNC machine operators in assessing product data before proceeded into CNC machining pro...

In this paper the application of parametric programming to CNC machining is discussed. As one of the less frequently utilized features of CNC machines, parametric programming has the potential to increase the efficiency of CNC operations. This feature is particularly beneficial to companies with group technology manufacturing where parts with similar design or operational requirements are proce...