Sister chromatids are preferred substrates for recombinational repair after cells are exposed to DNA damage. While some agents directly cause double-strand breaks (DSBs), others form DNA base adducts which stall or impede the DNA replication fork. We asked which types of DNA damage can stimulate SCE in budding yeast mutants defective in template switch mechanisms and whether PCNA polyubiquitina...

The sister chromatid exchange (SCE) frequencies of six freshly established and two old cell lines derived from patients with lymphatic tumors or leukemia were compared to the SCE rates of lymphoblastoid cell lines of normal controls. All cell lines from malignant tumors displayed significantly higher SCE values than the control lines. In general, the SCE rates seem to be correlated to the numbe...

Transcriptome alterations in liver and adipose tissue of cows with subclinical endometritis (SCE) at 29 d postpartum were evaluated. Bioinformatics analysis was performed using the Dynamic Impact Approach by means of KEGG and DAVID databases. Milk production, blood metabolites (non-esterified fatty acids, magnesium), and disease biomarkers (albumin, aspartate aminotransferase) did not differ gr...

BACKGROUND Silent cerebral events (SCE) have been identified on magnetic resonance imaging (MRI) in asymptomatic patients after atrial fibrillation (AF) ablation. Procedural determinants influencing the risk for SCE still remain unclear. OBJECTIVE Comparing the risk for SCE depending on exchanges of catheters (ExCath) over a single transseptal sheath. METHODS 88 Patients undergoing pulmonar...

BACKGROUND/OBJECTIVES This study investigated the antioxidant activities and hepatoprotective effects of Schisandra chinensis Baillon extract (SCE) against tert-butyl hydroperoxide (t-BHP)-induced oxidative hepatic damage in rats. MATERIALS/METHODS Sprague-Dawley (SD) rats were pretreated with SCE (300, 600, and 1,200 mg/kg BW) or saline once daily for 14 consecutive days. On day 14, each ani...

The Survey of Consumer Expectations (SCE) infers respondents’ inflation expectations from density forecasts. Using numeracy data and tests for coherence among 117,000 respondents to the SCE, I find that forecasts suffer non-negligible reporting bias selective nonresponse. A simple verbal question collected by SCE suffers neither these deficiencies so has better properties deliver an accurate sn...

An update is provided of Northern Hemisphere (NH) spring (March, April) snow cover extent (SCE) over the 1922–2010 period incorporating the new climate data record (CDR) version of the NOAA weekly SCE dataset, with annual 95% confidence intervals estimated from regression analysis and intercomparison of multiple datasets. The uncertainty analysis indicates a 95% confidence interval in NH spring...

The present study describes the establishment of both Band T-cell lines from the peripheral blood cells of two Bloom's syn drome (BS) patients and one healthy female by using EpsteinBarr (EBV) and adult T-cell leukemia viruses (ATLV). The cell lines from normal and BS subjects exhibited cell surface markers compatible with Band T-cell origin; in addition, the BS Band T-cell lines retained the o...